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- W2068442977 abstract "Abstract 1. 1. Two per cent atropine, topically applied to somatic sensory cortex, produced an increase in the size and diphasicity of evoked cortical potentials. It is concluded that atropine probably acts in deeper cortical layers by blocking a presumably cholinergic cortical tonic inhibitory system. 2. 2. By recording simultaneously from homologous motor and sensory areas, and applying atropine to the latter, it was found that atropine by itself was capable of facilitating the transmission of impulses in transcortical pathways in which activity had not previously been seen. 3. 3. Even after the maximal effect of atropine had been reached, topical application of prostigmine and acetylcholine subsequently could cause a marked further augmentation of the size and diphasicity of evoked responses. It is concluded that acetylcholine may be involved in neurohumoral transmission within specific afferent and other systems of the cerebral cortex." @default.
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- W2068442977 date "1955-11-01" @default.
- W2068442977 modified "2023-09-25" @default.
- W2068442977 title "Effects of atropine, prostigmine and acetylcholine on evoked cortical potentials" @default.
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- W2068442977 doi "https://doi.org/10.1016/0013-4694(55)90080-8" @default.
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