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- W2068446566 abstract "Chronic relapsing inflammatory optic neuropathy (CRION) is an entity that was described in 2003. Early recognition of patients suffering from CRION is relevant because of the associated risk for blindness if treated inappropriately. It seems timely to have a clinical review on this recently defined entity. A systematic literature review, irrespective of language, retrieved 22 case series and single reports describing 122 patients with CRION between 2003 and 2013. We review the epidemiology, diagnostic workup, differential diagnosis, and treatment (acute, intermediate, and long term) in view of the collective data. These data suggest that CRION is a distinct nosological entity, which is seronegative for anti-aquaporin four auto-antibodies and recognized by and managed through its dependency on immuno-suppression. Revised diagnostic criteria are proposed in light of the data compromising a critical discussion of relevant limitations." @default.
- W2068446566 created "2016-06-24" @default.
- W2068446566 creator A5030792843 @default.
- W2068446566 creator A5061751725 @default.
- W2068446566 date "2013-05-23" @default.
- W2068446566 modified "2023-09-27" @default.
- W2068446566 title "Chronic relapsing inflammatory optic neuropathy: a systematic review of 122 cases reported" @default.
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- W2068446566 doi "https://doi.org/10.1007/s00415-013-6957-4" @default.
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