FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068497867> ?p ?o ?g. }

• W2068497867 endingPage "143" @default.
• W2068497867 startingPage "133" @default.
• W2068497867 abstract "Dominant plant resistance genes are involved in the protection of plants against a wide variety of pathogens. Sequence analysis has revealed a variety of classes, often having domains in common. One commonly found region has come to be known as a putative nucleotide-binding site (NBS) due to the simple presence of sequence motifs. Until now, no experimental evidence has supported this idea. Here we suggest, as an alternative hypothesis, that part of this region is structurally homologous to the receiver domain common to many proteins of His-Asp phosphotransfer pathways. This conclusion is based on sequence analysis, threading experiments, and the construction of a molecular model of one domain that performs well against structure validation tools. The new hypothesis, in contrast to the NBS hypothesis, can explain the devastating effect of a Thr→Ala mutation in a well-characterized resistance gene product. According to the new hypothesis, regions located N-terminal and C-terminal to the modeled portion, containing highly conserved sequence motifs, could form a separate domain. Proteins 2000;41:133–143. © 2000 Wiley-Liss, Inc." @default.
• W2068497867 created "2016-06-24" @default.
• W2068497867 creator A5009636964 @default.
• W2068497867 creator A5048124538 @default.
• W2068497867 creator A5057166621 @default.
• W2068497867 date "2000-01-01" @default.
• W2068497867 modified "2023-09-25" @default.
• W2068497867 title "Structural modeling of a plant disease resistance gene product domain" @default.
• W2068497867 cites W1520416422 @default.
• W2068497867 cites W1604223977 @default.
• W2068497867 cites W1838580001 @default.
• W2068497867 cites W1966975589 @default.
• W2068497867 cites W1971085025 @default.
• W2068497867 cites W1973491891 @default.
• W2068497867 cites W1973891844 @default.
• W2068497867 cites W1976422615 @default.
• W2068497867 cites W1978024591 @default.
• W2068497867 cites W1979517563 @default.
• W2068497867 cites W1979801072 @default.
• W2068497867 cites W1980791071 @default.
• W2068497867 cites W1983558037 @default.
• W2068497867 cites W1985744441 @default.
• W2068497867 cites W1986191025 @default.
• W2068497867 cites W1989581558 @default.
• W2068497867 cites W1989632089 @default.
• W2068497867 cites W1993902553 @default.
• W2068497867 cites W1995808557 @default.
• W2068497867 cites W1996642492 @default.
• W2068497867 cites W2000646546 @default.
• W2068497867 cites W2000965923 @default.
• W2068497867 cites W2001985302 @default.
• W2068497867 cites W2005120335 @default.
• W2068497867 cites W2015532251 @default.
• W2068497867 cites W2016737807 @default.
• W2068497867 cites W2019207089 @default.
• W2068497867 cites W2019858721 @default.
• W2068497867 cites W2028231353 @default.
• W2068497867 cites W2033982014 @default.
• W2068497867 cites W2034100527 @default.
• W2068497867 cites W2035445202 @default.
• W2068497867 cites W2041797655 @default.
• W2068497867 cites W2045103836 @default.
• W2068497867 cites W2048205348 @default.
• W2068497867 cites W2050821290 @default.
• W2068497867 cites W2059856607 @default.
• W2068497867 cites W2065283382 @default.
• W2068497867 cites W2069185339 @default.
• W2068497867 cites W2071486470 @default.
• W2068497867 cites W2071769268 @default.
• W2068497867 cites W2076479752 @default.
• W2068497867 cites W2091969321 @default.
• W2068497867 cites W2098439072 @default.
• W2068497867 cites W2100874068 @default.
• W2068497867 cites W2106154817 @default.
• W2068497867 cites W2108067237 @default.
• W2068497867 cites W2113619956 @default.
• W2068497867 cites W2117019496 @default.
• W2068497867 cites W2119564924 @default.
• W2068497867 cites W2120877947 @default.
• W2068497867 cites W2122583048 @default.
• W2068497867 cites W2127096639 @default.
• W2068497867 cites W2130920644 @default.
• W2068497867 cites W2139279375 @default.
• W2068497867 cites W2139927250 @default.
• W2068497867 cites W2140244239 @default.
• W2068497867 cites W2140514445 @default.
• W2068497867 cites W2142193549 @default.
• W2068497867 cites W2144483796 @default.
• W2068497867 cites W2145499901 @default.
• W2068497867 cites W2149612698 @default.
• W2068497867 cites W2152326664 @default.
• W2068497867 cites W2155611044 @default.
• W2068497867 cites W2155923302 @default.
• W2068497867 cites W2157165549 @default.
• W2068497867 cites W2158714788 @default.
• W2068497867 cites W2162171603 @default.
• W2068497867 cites W2167950038 @default.
• W2068497867 cites W2170234851 @default.
• W2068497867 cites W3023114460 @default.
• W2068497867 cites W4205995961 @default.
• W2068497867 cites W4231445346 @default.
• W2068497867 cites W4239452276 @default.
• W2068497867 cites W4240185076 @default.
• W2068497867 cites W4241855343 @default.
• W2068497867 cites W4245658862 @default.
• W2068497867 cites W4247866849 @default.
• W2068497867 cites W4250602387 @default.
• W2068497867 cites W4317929372 @default.
• W2068497867 doi "https://doi.org/10.1002/1097-0134(20001001)41:1<133::aid-prot150>3.0.co;2-m" @default.
• W2068497867 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10944400" @default.
• W2068497867 hasPublicationYear "2000" @default.
• W2068497867 type Work @default.
• W2068497867 sameAs 2068497867 @default.
• W2068497867 citedByCount "17" @default.
• W2068497867 countsByYear W20684978672012 @default.
• W2068497867 countsByYear W20684978672013 @default.
• W2068497867 countsByYear W20684978672019 @default.
• W2068497867 crossrefType "journal-article" @default.

• next