FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068506787> ?p ?o ?g. }

• W2068506787 endingPage "183" @default.
• W2068506787 startingPage "169" @default.
• W2068506787 abstract "In skeletal and cardiac muscle, calcium release from the sarcoplasmic reticulum, leading to contraction, often results in calcium sparks. Because sparks are recorded by confocal microscopy in line-scanning mode, their measured amplitude depends on their true amplitude and the position of the spark relative to the scanned line. We present a method to derive from measured amplitude histograms the actual distribution of spark amplitudes. The method worked well when tested on simulated distributions of experimental sparks. Applied to massive numbers of sparks imaged in frog skeletal muscle under voltage clamp in reference conditions, the method yielded either a decaying amplitude distribution (6 cells) or one with a central mode (5 cells). Caffeine at 0.5 or 1 mM reversibly enhanced this mode (5 cells) or induced its appearance (4 cells). The occurrence of a mode in the amplitude distribution was highly correlated with the presence of a mode in the distribution of spark rise times or in the joint distribution of rise times and spatial widths. If sparks were produced by individual Markovian release channels evolving reversibly, they should not have a preferred rise time or amplitude. Channel groups, instead, could cooperate allosterically or through their calcium sensitivity, and give rise to a stereotyped amplitude in their collective spark." @default.
• W2068506787 created "2016-06-24" @default.
• W2068506787 creator A5011714569 @default.
• W2068506787 creator A5012744866 @default.
• W2068506787 creator A5051311745 @default.
• W2068506787 creator A5064156865 @default.
• W2068506787 creator A5075596073 @default.
• W2068506787 creator A5076736316 @default.
• W2068506787 creator A5079194878 @default.
• W2068506787 date "2001-01-01" @default.
• W2068506787 modified "2023-10-18" @default.
• W2068506787 title "A Preferred Amplitude of Calcium Sparks in Skeletal Muscle" @default.
• W2068506787 cites W1545077229 @default.
• W2068506787 cites W1965021019 @default.
• W2068506787 cites W1975200874 @default.
• W2068506787 cites W1977464281 @default.
• W2068506787 cites W1984280849 @default.
• W2068506787 cites W1984804294 @default.
• W2068506787 cites W1994460255 @default.
• W2068506787 cites W1997403679 @default.
• W2068506787 cites W2002046920 @default.
• W2068506787 cites W2002741066 @default.
• W2068506787 cites W2020169832 @default.
• W2068506787 cites W2020289409 @default.
• W2068506787 cites W2029959104 @default.
• W2068506787 cites W2043590623 @default.
• W2068506787 cites W2044578504 @default.
• W2068506787 cites W2046475516 @default.
• W2068506787 cites W2049939382 @default.
• W2068506787 cites W2050553914 @default.
• W2068506787 cites W2054225000 @default.
• W2068506787 cites W2058585388 @default.
• W2068506787 cites W2069230499 @default.
• W2068506787 cites W2069892277 @default.
• W2068506787 cites W2095152173 @default.
• W2068506787 cites W2096884612 @default.
• W2068506787 cites W2122031584 @default.
• W2068506787 cites W2126674741 @default.
• W2068506787 cites W2127542820 @default.
• W2068506787 cites W2129307413 @default.
• W2068506787 cites W2133064441 @default.
• W2068506787 cites W2135106801 @default.
• W2068506787 cites W2138958648 @default.
• W2068506787 cites W2161957047 @default.
• W2068506787 cites W2162047059 @default.
• W2068506787 doi "https://doi.org/10.1016/s0006-3495(01)76005-5" @default.
• W2068506787 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1301224" @default.
• W2068506787 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11159393" @default.
• W2068506787 hasPublicationYear "2001" @default.
• W2068506787 type Work @default.
• W2068506787 sameAs 2068506787 @default.
• W2068506787 citedByCount "37" @default.
• W2068506787 countsByYear W20685067872012 @default.
• W2068506787 countsByYear W20685067872013 @default.
• W2068506787 countsByYear W20685067872014 @default.
• W2068506787 countsByYear W20685067872015 @default.
• W2068506787 countsByYear W20685067872018 @default.
• W2068506787 countsByYear W20685067872022 @default.
• W2068506787 crossrefType "journal-article" @default.
• W2068506787 hasAuthorship W2068506787A5011714569 @default.
• W2068506787 hasAuthorship W2068506787A5012744866 @default.
• W2068506787 hasAuthorship W2068506787A5051311745 @default.
• W2068506787 hasAuthorship W2068506787A5064156865 @default.
• W2068506787 hasAuthorship W2068506787A5075596073 @default.
• W2068506787 hasAuthorship W2068506787A5076736316 @default.
• W2068506787 hasAuthorship W2068506787A5079194878 @default.
• W2068506787 hasBestOaLocation W20685067871 @default.
• W2068506787 hasConcept C105702510 @default.
• W2068506787 hasConcept C120665830 @default.
• W2068506787 hasConcept C121332964 @default.
• W2068506787 hasConcept C12554922 @default.
• W2068506787 hasConcept C134018914 @default.
• W2068506787 hasConcept C158617107 @default.
• W2068506787 hasConcept C178790620 @default.
• W2068506787 hasConcept C180205008 @default.
• W2068506787 hasConcept C185592680 @default.
• W2068506787 hasConcept C2778500429 @default.
• W2068506787 hasConcept C2779959927 @default.
• W2068506787 hasConcept C46141821 @default.
• W2068506787 hasConcept C519063684 @default.
• W2068506787 hasConcept C55493867 @default.
• W2068506787 hasConcept C86803240 @default.
• W2068506787 hasConceptScore W2068506787C105702510 @default.
• W2068506787 hasConceptScore W2068506787C120665830 @default.
• W2068506787 hasConceptScore W2068506787C121332964 @default.
• W2068506787 hasConceptScore W2068506787C12554922 @default.
• W2068506787 hasConceptScore W2068506787C134018914 @default.
• W2068506787 hasConceptScore W2068506787C158617107 @default.
• W2068506787 hasConceptScore W2068506787C178790620 @default.
• W2068506787 hasConceptScore W2068506787C180205008 @default.
• W2068506787 hasConceptScore W2068506787C185592680 @default.
• W2068506787 hasConceptScore W2068506787C2778500429 @default.
• W2068506787 hasConceptScore W2068506787C2779959927 @default.
• W2068506787 hasConceptScore W2068506787C46141821 @default.
• W2068506787 hasConceptScore W2068506787C519063684 @default.
• W2068506787 hasConceptScore W2068506787C55493867 @default.
• W2068506787 hasConceptScore W2068506787C86803240 @default.
• W2068506787 hasIssue "1" @default.

• next