Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068552008> ?p ?o ?g. }
- W2068552008 endingPage "12219" @default.
- W2068552008 startingPage "12212" @default.
- W2068552008 abstract "Polymer nanocapsules play an increasingly important role for drug delivery applications. Layer-by-layer (LbL) templated synthesis has received the widest attention to fabricate polymer nanocapsules. However, for drug delivery applications, the LbL approach may not necessarily offer the optimum nanocapsules. We make the first attempt to compare the LbL approach with a more recently developed solid core/mesoporous shell (SC/MS) templated approach in context of their suitability for construction of sub-500 nm sized capsules for drug delivery applications. The nanocapsules of chitosan, poly(allylamine hydrochloride) (PAH), and poly(sodium 4-styrenesulfonate) (PSS) are fabricated using LbL and SC/MS templating approaches and loaded with curcumin, a model lipophilic anticancer drug. The influence of the templating approach on capsule aggregation, polymer loading, drug loading, cellular uptake, and therapeutic efficacy against MCF-7 breast cancer cells is compared in an effort to identify the most suitable fabrication method and polymer material for drug delivery applications. In combination, among different tested nanocapsules, chitosan nanocapsules fabricated using the SC/MS approach are found to be the most promising candidate that demonstrates the optimum cytotoxic efficiency and significant potential for drug delivery." @default.
- W2068552008 created "2016-06-24" @default.
- W2068552008 creator A5028533016 @default.
- W2068552008 creator A5054308329 @default.
- W2068552008 creator A5062644316 @default.
- W2068552008 creator A5083599930 @default.
- W2068552008 creator A5087855547 @default.
- W2068552008 date "2013-09-17" @default.
- W2068552008 modified "2023-09-27" @default.
- W2068552008 title "Role of the Templating Approach in Influencing the Suitability of Polymeric Nanocapsules for Drug Delivery: LbL vs SC/MS" @default.
- W2068552008 cites W1971992993 @default.
- W2068552008 cites W1977362354 @default.
- W2068552008 cites W1977856527 @default.
- W2068552008 cites W1982505831 @default.
- W2068552008 cites W1983055717 @default.
- W2068552008 cites W1983331263 @default.
- W2068552008 cites W1996998905 @default.
- W2068552008 cites W2005062196 @default.
- W2068552008 cites W2010860761 @default.
- W2068552008 cites W2010908849 @default.
- W2068552008 cites W2014640355 @default.
- W2068552008 cites W2021701733 @default.
- W2068552008 cites W2021931700 @default.
- W2068552008 cites W2026494961 @default.
- W2068552008 cites W2029851331 @default.
- W2068552008 cites W2031820392 @default.
- W2068552008 cites W2035544537 @default.
- W2068552008 cites W2036636807 @default.
- W2068552008 cites W2042274498 @default.
- W2068552008 cites W2043502318 @default.
- W2068552008 cites W2049312803 @default.
- W2068552008 cites W2051667187 @default.
- W2068552008 cites W2051805600 @default.
- W2068552008 cites W2052884059 @default.
- W2068552008 cites W2056709531 @default.
- W2068552008 cites W2058549300 @default.
- W2068552008 cites W2059298390 @default.
- W2068552008 cites W2064845643 @default.
- W2068552008 cites W2064848737 @default.
- W2068552008 cites W2065901663 @default.
- W2068552008 cites W2072175441 @default.
- W2068552008 cites W2093676765 @default.
- W2068552008 cites W2147485515 @default.
- W2068552008 cites W2165984057 @default.
- W2068552008 cites W2167576655 @default.
- W2068552008 cites W2170750193 @default.
- W2068552008 cites W2171126112 @default.
- W2068552008 cites W2317575211 @default.
- W2068552008 doi "https://doi.org/10.1021/la4024103" @default.
- W2068552008 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23998648" @default.
- W2068552008 hasPublicationYear "2013" @default.
- W2068552008 type Work @default.
- W2068552008 sameAs 2068552008 @default.
- W2068552008 citedByCount "14" @default.
- W2068552008 countsByYear W20685520082015 @default.
- W2068552008 countsByYear W20685520082016 @default.
- W2068552008 countsByYear W20685520082018 @default.
- W2068552008 countsByYear W20685520082020 @default.
- W2068552008 countsByYear W20685520082021 @default.
- W2068552008 countsByYear W20685520082023 @default.
- W2068552008 crossrefType "journal-article" @default.
- W2068552008 hasAuthorship W2068552008A5028533016 @default.
- W2068552008 hasAuthorship W2068552008A5054308329 @default.
- W2068552008 hasAuthorship W2068552008A5062644316 @default.
- W2068552008 hasAuthorship W2068552008A5083599930 @default.
- W2068552008 hasAuthorship W2068552008A5087855547 @default.
- W2068552008 hasConcept C153356533 @default.
- W2068552008 hasConcept C155672457 @default.
- W2068552008 hasConcept C159985019 @default.
- W2068552008 hasConcept C171250308 @default.
- W2068552008 hasConcept C178790620 @default.
- W2068552008 hasConcept C185592680 @default.
- W2068552008 hasConcept C192562407 @default.
- W2068552008 hasConcept C204399865 @default.
- W2068552008 hasConcept C2778927588 @default.
- W2068552008 hasConcept C2779732960 @default.
- W2068552008 hasConcept C2779820397 @default.
- W2068552008 hasConcept C521977710 @default.
- W2068552008 hasConceptScore W2068552008C153356533 @default.
- W2068552008 hasConceptScore W2068552008C155672457 @default.
- W2068552008 hasConceptScore W2068552008C159985019 @default.
- W2068552008 hasConceptScore W2068552008C171250308 @default.
- W2068552008 hasConceptScore W2068552008C178790620 @default.
- W2068552008 hasConceptScore W2068552008C185592680 @default.
- W2068552008 hasConceptScore W2068552008C192562407 @default.
- W2068552008 hasConceptScore W2068552008C204399865 @default.
- W2068552008 hasConceptScore W2068552008C2778927588 @default.
- W2068552008 hasConceptScore W2068552008C2779732960 @default.
- W2068552008 hasConceptScore W2068552008C2779820397 @default.
- W2068552008 hasConceptScore W2068552008C521977710 @default.
- W2068552008 hasIssue "39" @default.
- W2068552008 hasLocation W20685520081 @default.
- W2068552008 hasLocation W20685520082 @default.
- W2068552008 hasOpenAccess W2068552008 @default.
- W2068552008 hasPrimaryLocation W20685520081 @default.
- W2068552008 hasRelatedWork W1973378461 @default.
- W2068552008 hasRelatedWork W2072018844 @default.
- W2068552008 hasRelatedWork W2081258761 @default.