Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068559547> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2068559547 endingPage "93" @default.
- W2068559547 startingPage "88" @default.
- W2068559547 abstract "Patients with essential thrombocythemia (ET) are at increased risk for large-vessel and microvascular thrombosis, presumably because of abnormal platelet number and function. To determine if another hemostatic abnormality might contribute to this thrombotic risk, we investigated protein C and protein S and the fibrinolytic system in four patients with ET. The patients segregated into two distinct groups. The first group consisted of two patients with moderate thrombocytosis who were without thrombotic symptoms and who had normal protein S and protein C and normal fibrinolysis. The second group consisted of two patients with mild to moderate thrombocytosis and thrombosis. Both these latter two patients had abnormalities in protein S. The first patient had only 31% free protein S and 67% total protein S, with normal protein C and normal fibrinolysis. Following treatment, vasoocclusive symptoms resolved and platelet count decreased, but protein S remained low (28% free protein S). The second patient in this group had only 35% total protein S at initial study. Other hemostatic abnormalities were also present. Following treatment, symptoms resolved and protein S returned to normal. Based on this limited series, it appears that, in some patients with ET, thrombotic phenomena may be due to the presence of a second hemostatic abnormality in addition to the high platelet count and abnormal platelet function. This abnormality may be acquired as part of the disease process. Some of these abnormalities may be corrected following treatment." @default.
- W2068559547 created "2016-06-24" @default.
- W2068559547 creator A5034020073 @default.
- W2068559547 creator A5038563211 @default.
- W2068559547 date "1989-10-01" @default.
- W2068559547 modified "2023-09-24" @default.
- W2068559547 title "Low protein s in essential thrombocythemia with thrombosis" @default.
- W2068559547 cites W1578912075 @default.
- W2068559547 cites W167119892 @default.
- W2068559547 cites W1966406554 @default.
- W2068559547 cites W1969382756 @default.
- W2068559547 cites W1986995565 @default.
- W2068559547 cites W1987940917 @default.
- W2068559547 cites W2000055469 @default.
- W2068559547 cites W2009955884 @default.
- W2068559547 cites W2009961863 @default.
- W2068559547 cites W2010097797 @default.
- W2068559547 cites W2012619506 @default.
- W2068559547 cites W2016710965 @default.
- W2068559547 cites W2034571640 @default.
- W2068559547 cites W2039313371 @default.
- W2068559547 cites W2043045115 @default.
- W2068559547 cites W2047192695 @default.
- W2068559547 cites W2052905336 @default.
- W2068559547 cites W2077999696 @default.
- W2068559547 cites W2086386527 @default.
- W2068559547 cites W2095188600 @default.
- W2068559547 cites W2115180484 @default.
- W2068559547 cites W2134608013 @default.
- W2068559547 cites W2400531896 @default.
- W2068559547 cites W2419191488 @default.
- W2068559547 cites W2420888120 @default.
- W2068559547 cites W362194484 @default.
- W2068559547 cites W41918077 @default.
- W2068559547 cites W4302557384 @default.
- W2068559547 doi "https://doi.org/10.1002/ajh.2830320203" @default.
- W2068559547 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2527003" @default.
- W2068559547 hasPublicationYear "1989" @default.
- W2068559547 type Work @default.
- W2068559547 sameAs 2068559547 @default.
- W2068559547 citedByCount "21" @default.
- W2068559547 countsByYear W20685595472014 @default.
- W2068559547 crossrefType "journal-article" @default.
- W2068559547 hasAuthorship W2068559547A5034020073 @default.
- W2068559547 hasAuthorship W2068559547A5038563211 @default.
- W2068559547 hasConcept C118552586 @default.
- W2068559547 hasConcept C126322002 @default.
- W2068559547 hasConcept C2776135265 @default.
- W2068559547 hasConcept C2776825266 @default.
- W2068559547 hasConcept C2779788118 @default.
- W2068559547 hasConcept C2780868729 @default.
- W2068559547 hasConcept C2781057849 @default.
- W2068559547 hasConcept C2781287897 @default.
- W2068559547 hasConcept C50965678 @default.
- W2068559547 hasConcept C71924100 @default.
- W2068559547 hasConcept C89560881 @default.
- W2068559547 hasConcept C90924648 @default.
- W2068559547 hasConceptScore W2068559547C118552586 @default.
- W2068559547 hasConceptScore W2068559547C126322002 @default.
- W2068559547 hasConceptScore W2068559547C2776135265 @default.
- W2068559547 hasConceptScore W2068559547C2776825266 @default.
- W2068559547 hasConceptScore W2068559547C2779788118 @default.
- W2068559547 hasConceptScore W2068559547C2780868729 @default.
- W2068559547 hasConceptScore W2068559547C2781057849 @default.
- W2068559547 hasConceptScore W2068559547C2781287897 @default.
- W2068559547 hasConceptScore W2068559547C50965678 @default.
- W2068559547 hasConceptScore W2068559547C71924100 @default.
- W2068559547 hasConceptScore W2068559547C89560881 @default.
- W2068559547 hasConceptScore W2068559547C90924648 @default.
- W2068559547 hasIssue "2" @default.
- W2068559547 hasLocation W20685595471 @default.
- W2068559547 hasLocation W20685595472 @default.
- W2068559547 hasOpenAccess W2068559547 @default.
- W2068559547 hasPrimaryLocation W20685595471 @default.
- W2068559547 hasRelatedWork W1983645734 @default.
- W2068559547 hasRelatedWork W1999955631 @default.
- W2068559547 hasRelatedWork W2022307701 @default.
- W2068559547 hasRelatedWork W2068559547 @default.
- W2068559547 hasRelatedWork W2069343109 @default.
- W2068559547 hasRelatedWork W2110966022 @default.
- W2068559547 hasRelatedWork W2354812008 @default.
- W2068559547 hasRelatedWork W2413932575 @default.
- W2068559547 hasRelatedWork W2419051813 @default.
- W2068559547 hasRelatedWork W3187992395 @default.
- W2068559547 hasVolume "32" @default.
- W2068559547 isParatext "false" @default.
- W2068559547 isRetracted "false" @default.
- W2068559547 magId "2068559547" @default.
- W2068559547 workType "article" @default.