Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068574785> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2068574785 endingPage "1048" @default.
- W2068574785 startingPage "1042" @default.
- W2068574785 abstract "The chemokine eotaxin has been implicated in airway eosinophilia in atopic asthma. We have compared airway eosinophils and eotaxin expression in induced sputum from well-matched atopic and nonatopic asthmatics.Eosinophil numbers, eosinophil cationic protein (ECP), and the expression of eotaxin were examined in induced sputum from atopic asthmatics (AA = 11), nonatopic asthmatics (NAA = 11), and atopic (AC = 12) and normal (NC = 10) controls. Slides were prepared for differential cell counts by Romanowsky stain, and ECP levels were measured by RIA. Eotaxin expression was detected by in situ hybridization, with 35S-labelled riboprobes and immunocytochemistry.The numbers of eosinophils and ECP concentration were increased in the sputum of AA and NAA compared with AC and NC (P < 0.05). The numbers of eotaxin mRNA+ and immunoreactive cells were increased in NAA, but not AA, when compared with controls (P < 0.05). Eotaxin immunoreactive cells in NAA were significantly higher than in AA (P < 0.05). Eotaxin was expressed predominantly by macrophages, eosinophils, and epithelial cells. In NAA, but not AA, the numbers of eotaxin mRNA+ cells were correlated with histamine PC20 (r = -0.81, P < 0.01) and eosinophil numbers in sputum (r = 0.7, P < 0.05).Eotaxin production by macrophages, eosinophils, and epithelial cells may play a more pronounced role in airway eosinophilia in nonatopic than in atopic asthma." @default.
- W2068574785 created "2016-06-24" @default.
- W2068574785 creator A5012458363 @default.
- W2068574785 creator A5017947009 @default.
- W2068574785 creator A5023307885 @default.
- W2068574785 creator A5041987898 @default.
- W2068574785 creator A5043703051 @default.
- W2068574785 creator A5057339248 @default.
- W2068574785 date "2000-11-01" @default.
- W2068574785 modified "2023-09-26" @default.
- W2068574785 title "Expression of eotaxin in induced sputum of atopic and nonatopic asthmatics" @default.
- W2068574785 cites W1657740120 @default.
- W2068574785 cites W1967777975 @default.
- W2068574785 cites W1971148540 @default.
- W2068574785 cites W1978403614 @default.
- W2068574785 cites W1983865870 @default.
- W2068574785 cites W1999172455 @default.
- W2068574785 cites W2021451119 @default.
- W2068574785 cites W2025442831 @default.
- W2068574785 cites W2040836319 @default.
- W2068574785 cites W2045417854 @default.
- W2068574785 cites W2051948045 @default.
- W2068574785 cites W2068520333 @default.
- W2068574785 cites W2071199365 @default.
- W2068574785 cites W2081323519 @default.
- W2068574785 cites W2095784197 @default.
- W2068574785 cites W2113736505 @default.
- W2068574785 cites W2119996406 @default.
- W2068574785 cites W2121935480 @default.
- W2068574785 cites W2153801667 @default.
- W2068574785 cites W2154302682 @default.
- W2068574785 cites W2167362392 @default.
- W2068574785 cites W2417303351 @default.
- W2068574785 cites W4256189644 @default.
- W2068574785 doi "https://doi.org/10.1034/j.1398-9995.2000.00764.x" @default.
- W2068574785 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11097314" @default.
- W2068574785 hasPublicationYear "2000" @default.
- W2068574785 type Work @default.
- W2068574785 sameAs 2068574785 @default.
- W2068574785 citedByCount "18" @default.
- W2068574785 countsByYear W20685747852016 @default.
- W2068574785 crossrefType "journal-article" @default.
- W2068574785 hasAuthorship W2068574785A5012458363 @default.
- W2068574785 hasAuthorship W2068574785A5017947009 @default.
- W2068574785 hasAuthorship W2068574785A5023307885 @default.
- W2068574785 hasAuthorship W2068574785A5041987898 @default.
- W2068574785 hasAuthorship W2068574785A5043703051 @default.
- W2068574785 hasAuthorship W2068574785A5057339248 @default.
- W2068574785 hasConcept C13373296 @default.
- W2068574785 hasConcept C142724271 @default.
- W2068574785 hasConcept C181901479 @default.
- W2068574785 hasConcept C203014093 @default.
- W2068574785 hasConcept C2776042228 @default.
- W2068574785 hasConcept C2776301714 @default.
- W2068574785 hasConcept C2776914184 @default.
- W2068574785 hasConcept C2777037409 @default.
- W2068574785 hasConcept C2777129736 @default.
- W2068574785 hasConcept C2777716647 @default.
- W2068574785 hasConcept C2778690821 @default.
- W2068574785 hasConcept C2781069245 @default.
- W2068574785 hasConcept C71924100 @default.
- W2068574785 hasConcept C74172505 @default.
- W2068574785 hasConcept C88675164 @default.
- W2068574785 hasConceptScore W2068574785C13373296 @default.
- W2068574785 hasConceptScore W2068574785C142724271 @default.
- W2068574785 hasConceptScore W2068574785C181901479 @default.
- W2068574785 hasConceptScore W2068574785C203014093 @default.
- W2068574785 hasConceptScore W2068574785C2776042228 @default.
- W2068574785 hasConceptScore W2068574785C2776301714 @default.
- W2068574785 hasConceptScore W2068574785C2776914184 @default.
- W2068574785 hasConceptScore W2068574785C2777037409 @default.
- W2068574785 hasConceptScore W2068574785C2777129736 @default.
- W2068574785 hasConceptScore W2068574785C2777716647 @default.
- W2068574785 hasConceptScore W2068574785C2778690821 @default.
- W2068574785 hasConceptScore W2068574785C2781069245 @default.
- W2068574785 hasConceptScore W2068574785C71924100 @default.
- W2068574785 hasConceptScore W2068574785C74172505 @default.
- W2068574785 hasConceptScore W2068574785C88675164 @default.
- W2068574785 hasIssue "11" @default.
- W2068574785 hasLocation W20685747851 @default.
- W2068574785 hasLocation W20685747852 @default.
- W2068574785 hasOpenAccess W2068574785 @default.
- W2068574785 hasPrimaryLocation W20685747851 @default.
- W2068574785 hasRelatedWork W2014078838 @default.
- W2068574785 hasRelatedWork W2046818609 @default.
- W2068574785 hasRelatedWork W2055390361 @default.
- W2068574785 hasRelatedWork W2063644977 @default.
- W2068574785 hasRelatedWork W2066810707 @default.
- W2068574785 hasRelatedWork W2068574785 @default.
- W2068574785 hasRelatedWork W2128413639 @default.
- W2068574785 hasRelatedWork W2132158328 @default.
- W2068574785 hasRelatedWork W2808675497 @default.
- W2068574785 hasRelatedWork W35794083 @default.
- W2068574785 hasVolume "55" @default.
- W2068574785 isParatext "false" @default.
- W2068574785 isRetracted "false" @default.
- W2068574785 magId "2068574785" @default.
- W2068574785 workType "article" @default.