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- W2068602144 abstract "A male zebra finch learns a song by listening to a tutor, but song learning is normally restricted to a critical period in juvenile development. Here we identify an RNA whose expression in the song control circuit is altered during this critical period. The RNA encodes a soluble presynaptic protein that forms a predicted amphipathic alpha helix typical of the lipid-binding domain in apolipoproteins. We show this protein, which we call synelfin, to be the homolog of the human non-A beta component (and its precursor) recently purified from Alzheimer's disease amyloid. We suggest this highly conserved protein may serve a novel function critical to the regulation of vertebrate neural plasticity." @default.
- W2068602144 created "2016-06-24" @default.
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- W2068602144 date "1995-08-01" @default.
- W2068602144 modified "2023-10-10" @default.
- W2068602144 title "Characterization of a novel protein regulated during the critical period for song learning in the zebra finch" @default.
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- W2068602144 doi "https://doi.org/10.1016/0896-6273(95)90040-3" @default.
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