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• W2068602562 endingPage "4436" @default.
• W2068602562 startingPage "4428" @default.
• W2068602562 abstract "Vesicles containing ternary mixtures of diphytanoylphosphatidylcholine, dipalmitoylphosphatidylcholine (DPPC), and cholesterol produce coexisting liquid phases over an unusually large range of temperature and composition. Liquid domains persist well above the DPPC chain melting temperature (41°C), resulting in a closed-loop miscibility gap bounded by two critical points at fixed temperature. Quantitative tie-lines are determined directly from 2H NMR spectra using a novel analysis, and are found to connect a liquid-disordered phase rich in diphytanoyl PC with a liquid-ordered phase rich in DPPC. The direction of the tie-lines implies that binary DPPC/cholesterol mixtures are in one uniform phase above 41°C. All 2H NMR results for tie-lines are verified by independent fluorescence microscopy results." @default.
• W2068602562 created "2016-06-24" @default.
• W2068602562 creator A5027410618 @default.
• W2068602562 creator A5028518958 @default.
• W2068602562 creator A5052880769 @default.
• W2068602562 date "2006-06-01" @default.
• W2068602562 modified "2023-09-25" @default.
• W2068602562 title "Closed-Loop Miscibility Gap and Quantitative Tie-Lines in Ternary Membranes Containing Diphytanoyl PC" @default.
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• W2068602562 doi "https://doi.org/10.1529/biophysj.105.080283" @default.
• W2068602562 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1471848" @default.
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• W2068602562 hasPublicationYear "2006" @default.
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