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- W2068602891 abstract "Purpose To determine the prevalence of age-related macular degeneration in the Age, Gene/Environment Susceptibility - Reykjavik Study.Methods The random sample includes individuals born between 1907 and 1935 who were recruited to participate from 2002-2006. 5272 participated in the 3rd follow-up visit which included an eye examination. After a maximum dilatation of the pupil all had a digital fundus photography centered on the macula. The photographs were graded by masked graders at the Wisconsin Ocular Epidemiology Grading Center using a modification of the Wisconsin Age-related Maculopathy Grading System.Results The participants were 67 years and older. There were 5138 right macular fundus photographs gradable for early age-related maculopathy (ARM). The prevalence of early ARM was 18.3% (95% CI 17.3-18.9). Among the participants 4.4% (95% CI 3.9-4.7) had late age-related macular degeneration (AMD). For pure geographic atrophy (GA) there were 5036 gradable photographs of the right macula and the prevalence was 2.1% (95% CI 1.7-2.3). Those with GA and also exudative AMD (mixed type) are not included in this category. For exudative late AMD there were 5152 gradable photographs of the right macula and the prevalence was 2.3% (95% CI 1.9-2.5). GA, when present, was located in the centre circle (foveal area) in the vast majority of cases.Conclusion We found a steep age-related increase in the prevalence of age-related maculopathy in this elderly white population and geographic atrophy was usually located in the foveal area. The prevalence was similar for both late types of age-related macular degeneration." @default.
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- W2068602891 date "2008-09-04" @default.
- W2068602891 modified "2023-10-16" @default.
- W2068602891 title "Prevalence of age-related macular degeneration in the AGES - Reykjavik Study" @default.
- W2068602891 doi "https://doi.org/10.1111/j.1755-3768.2008.485.x" @default.
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