Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068604977> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2068604977 endingPage "578" @default.
- W2068604977 startingPage "567" @default.
- W2068604977 abstract "Abstract Previous studies have shown that the carcinogen N -hydroxy-2-acetylaminofluorene is converted by one-electron oxidants to a free nitroxide radical which dismutates to N -acetoxy-2-acetylaminofluorene and 2-nitrosofluorene. The present study shows that the same oxidation can be achieved with horseradish peroxidase and H 2 O 2 . The free radical intermediate was detected by its ESR signal, and the yields of N -acetoxy-2-acetylaminofluorene and of 2-nitrosofluorene were determined under a number of conditions. Addition of tRNA to the reaction mixture containing N -acetoxy- N -2-acetyl[2′- 3 H]aminofluorene yielded tRNA-bound radioactivity; addition of guanosine yielded a reaction product which appears to be N -guanosin-8-yl)-2-acetylaminofluorene. The latter compound has previously been identified as a reaction product of N -acetoxy-2-acetylaminofluorene and guanosine. Preliminary attempts to demonstrate the formation of a nitroxide free radical or its dismutation products with rat liver mixed function oxidase systems were not successful." @default.
- W2068604977 created "2016-06-24" @default.
- W2068604977 creator A5025407234 @default.
- W2068604977 creator A5052781070 @default.
- W2068604977 date "1971-06-22" @default.
- W2068604977 modified "2023-09-26" @default.
- W2068604977 title "On the metabolic activation of the carcinogen N-hydroxy-N-2-acetylaminofluorene☆☆☆III. Oxidation with horseradish peroxidase to yield 2-nitrosofluorene and N-acetoxy-N-2-acetylaminofluorene" @default.
- W2068604977 cites W1495934178 @default.
- W2068604977 cites W1518238216 @default.
- W2068604977 cites W1547157661 @default.
- W2068604977 cites W1586956837 @default.
- W2068604977 cites W1605785947 @default.
- W2068604977 cites W1641834551 @default.
- W2068604977 cites W177448602 @default.
- W2068604977 cites W1844076469 @default.
- W2068604977 cites W1877422606 @default.
- W2068604977 cites W1969699612 @default.
- W2068604977 cites W1979863482 @default.
- W2068604977 cites W1984496444 @default.
- W2068604977 cites W2003030193 @default.
- W2068604977 cites W2044961016 @default.
- W2068604977 cites W2045863155 @default.
- W2068604977 cites W2052949624 @default.
- W2068604977 cites W2071756497 @default.
- W2068604977 cites W2075580314 @default.
- W2068604977 cites W2256439395 @default.
- W2068604977 cites W2282054059 @default.
- W2068604977 cites W2283438955 @default.
- W2068604977 cites W2408798039 @default.
- W2068604977 doi "https://doi.org/10.1016/0304-4165(71)90277-7" @default.
- W2068604977 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4330271" @default.
- W2068604977 hasPublicationYear "1971" @default.
- W2068604977 type Work @default.
- W2068604977 sameAs 2068604977 @default.
- W2068604977 citedByCount "83" @default.
- W2068604977 countsByYear W20686049772013 @default.
- W2068604977 crossrefType "journal-article" @default.
- W2068604977 hasAuthorship W2068604977A5025407234 @default.
- W2068604977 hasAuthorship W2068604977A5052781070 @default.
- W2068604977 hasConcept C114246631 @default.
- W2068604977 hasConcept C134121241 @default.
- W2068604977 hasConcept C162008176 @default.
- W2068604977 hasConcept C181199279 @default.
- W2068604977 hasConcept C185592680 @default.
- W2068604977 hasConcept C191897082 @default.
- W2068604977 hasConcept C192562407 @default.
- W2068604977 hasConcept C2777676563 @default.
- W2068604977 hasConcept C2779838395 @default.
- W2068604977 hasConcept C55493867 @default.
- W2068604977 hasConcept C87644729 @default.
- W2068604977 hasConceptScore W2068604977C114246631 @default.
- W2068604977 hasConceptScore W2068604977C134121241 @default.
- W2068604977 hasConceptScore W2068604977C162008176 @default.
- W2068604977 hasConceptScore W2068604977C181199279 @default.
- W2068604977 hasConceptScore W2068604977C185592680 @default.
- W2068604977 hasConceptScore W2068604977C191897082 @default.
- W2068604977 hasConceptScore W2068604977C192562407 @default.
- W2068604977 hasConceptScore W2068604977C2777676563 @default.
- W2068604977 hasConceptScore W2068604977C2779838395 @default.
- W2068604977 hasConceptScore W2068604977C55493867 @default.
- W2068604977 hasConceptScore W2068604977C87644729 @default.
- W2068604977 hasIssue "3" @default.
- W2068604977 hasLocation W20686049771 @default.
- W2068604977 hasLocation W20686049772 @default.
- W2068604977 hasOpenAccess W2068604977 @default.
- W2068604977 hasPrimaryLocation W20686049771 @default.
- W2068604977 hasRelatedWork W1974176317 @default.
- W2068604977 hasRelatedWork W1978181982 @default.
- W2068604977 hasRelatedWork W1989087169 @default.
- W2068604977 hasRelatedWork W1990473795 @default.
- W2068604977 hasRelatedWork W2011801069 @default.
- W2068604977 hasRelatedWork W2014168687 @default.
- W2068604977 hasRelatedWork W2043017646 @default.
- W2068604977 hasRelatedWork W2068380790 @default.
- W2068604977 hasRelatedWork W2068604977 @default.
- W2068604977 hasRelatedWork W2186129678 @default.
- W2068604977 hasVolume "237" @default.
- W2068604977 isParatext "false" @default.
- W2068604977 isRetracted "false" @default.
- W2068604977 magId "2068604977" @default.
- W2068604977 workType "article" @default.