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• W2068606947 endingPage "382" @default.
• W2068606947 startingPage "377" @default.
• W2068606947 abstract "T cells are activated by fragments of antigenic proteins bound to major histocompatibility complex (MHC) molecules and displayed on the cell surface. MHC class II proteins scavenge processed protein antigens from within endosomal compartments. The antigenic peptides are generated within these and other intracellular compartments using the array of proteolytic enzymes normally involved in terminal protein degradation. Antigen-presenting cells use different mechanisms to exploit and control the activity of these enzymes so as to ensure the generation of a wide variety of peptides, while preventing the destruction of antigenic epitopes by excessive proteolysis." @default.
• W2068606947 created "2016-06-24" @default.
• W2068606947 creator A5062829551 @default.
• W2068606947 creator A5078953147 @default.
• W2068606947 date "1997-10-01" @default.
• W2068606947 modified "2023-09-27" @default.
• W2068606947 title "Endosomal proteases and antigen processing" @default.
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• W2068606947 doi "https://doi.org/10.1016/s0968-0004(97)01116-x" @default.
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