Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068619783> ?p ?o ?g. }
- W2068619783 endingPage "521" @default.
- W2068619783 startingPage "513" @default.
- W2068619783 abstract "Here, we report the highly efficient in vitro differentiation of human bone marrow-derived mesenchymal stem/progenitor cells (MPCs) using a novel nanotechnology-based culture plate, nanoculture plate(®) (NCP). The NCP contains uneven microfabrications with diameters of ∼2-3 μm arranged in a honeycomb pattern on its culture surface, which is devoid of animal-derived protein sources. When human MPCs were subjected to three-dimensional (3D) culture using an NCP, they rapidly formed adhesive spheroids. We showed that adipogenic differentiation in NCP-mediated 3D cultures led to more rapid accumulation of triglycerides than that in two-dimensional cultures. During adipogenesis in 3D cultures, the rapid and intense induction of adipocyte-specific gene expressions, such as peroxisome proliferator-activated receptor γ (PPAR-γ), CCAAT-enhancer-binding protein α (C/EBP-α), adipocyte protein 2 (aP2), and adiponectin was observed. Together, these results indicate that this 3D culture system is suitable for the differentiation of human MPCs into adipogenic lineage, and could be applicable to adipose tissue engineering under xeno-free condition." @default.
- W2068619783 created "2016-06-24" @default.
- W2068619783 creator A5001561113 @default.
- W2068619783 creator A5003180057 @default.
- W2068619783 creator A5027421629 @default.
- W2068619783 creator A5031196947 @default.
- W2068619783 creator A5032975570 @default.
- W2068619783 creator A5033181376 @default.
- W2068619783 creator A5035249959 @default.
- W2068619783 creator A5052172218 @default.
- W2068619783 creator A5066995769 @default.
- W2068619783 creator A5073119979 @default.
- W2068619783 creator A5090276194 @default.
- W2068619783 date "2011-02-01" @default.
- W2068619783 modified "2023-10-16" @default.
- W2068619783 title "A Microfabricated Scaffold Induces the Spheroid Formation of Human Bone Marrow-Derived Mesenchymal Progenitor Cells and Promotes Efficient Adipogenic Differentiation" @default.
- W2068619783 cites W1972874402 @default.
- W2068619783 cites W1973744818 @default.
- W2068619783 cites W1977950302 @default.
- W2068619783 cites W1982561969 @default.
- W2068619783 cites W1983271466 @default.
- W2068619783 cites W1986433954 @default.
- W2068619783 cites W1987032519 @default.
- W2068619783 cites W1992677381 @default.
- W2068619783 cites W1996590094 @default.
- W2068619783 cites W2005902803 @default.
- W2068619783 cites W2008613699 @default.
- W2068619783 cites W2014673628 @default.
- W2068619783 cites W2015496410 @default.
- W2068619783 cites W2021765303 @default.
- W2068619783 cites W2024789275 @default.
- W2068619783 cites W2027141641 @default.
- W2068619783 cites W2036220883 @default.
- W2068619783 cites W2054507508 @default.
- W2068619783 cites W2059066863 @default.
- W2068619783 cites W2062741385 @default.
- W2068619783 cites W2065571904 @default.
- W2068619783 cites W2070190764 @default.
- W2068619783 cites W2072261072 @default.
- W2068619783 cites W2072386632 @default.
- W2068619783 cites W2085711413 @default.
- W2068619783 cites W2102525693 @default.
- W2068619783 cites W2105801231 @default.
- W2068619783 cites W2107649335 @default.
- W2068619783 cites W2110050415 @default.
- W2068619783 cites W2131388270 @default.
- W2068619783 cites W2133588934 @default.
- W2068619783 cites W2134208433 @default.
- W2068619783 cites W2148386717 @default.
- W2068619783 cites W2159999899 @default.
- W2068619783 doi "https://doi.org/10.1089/ten.tea.2009.0810" @default.
- W2068619783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20818998" @default.
- W2068619783 hasPublicationYear "2011" @default.
- W2068619783 type Work @default.
- W2068619783 sameAs 2068619783 @default.
- W2068619783 citedByCount "57" @default.
- W2068619783 countsByYear W20686197832012 @default.
- W2068619783 countsByYear W20686197832013 @default.
- W2068619783 countsByYear W20686197832014 @default.
- W2068619783 countsByYear W20686197832015 @default.
- W2068619783 countsByYear W20686197832016 @default.
- W2068619783 countsByYear W20686197832017 @default.
- W2068619783 countsByYear W20686197832018 @default.
- W2068619783 countsByYear W20686197832019 @default.
- W2068619783 countsByYear W20686197832020 @default.
- W2068619783 countsByYear W20686197832021 @default.
- W2068619783 countsByYear W20686197832022 @default.
- W2068619783 crossrefType "journal-article" @default.
- W2068619783 hasAuthorship W2068619783A5001561113 @default.
- W2068619783 hasAuthorship W2068619783A5003180057 @default.
- W2068619783 hasAuthorship W2068619783A5027421629 @default.
- W2068619783 hasAuthorship W2068619783A5031196947 @default.
- W2068619783 hasAuthorship W2068619783A5032975570 @default.
- W2068619783 hasAuthorship W2068619783A5033181376 @default.
- W2068619783 hasAuthorship W2068619783A5035249959 @default.
- W2068619783 hasAuthorship W2068619783A5052172218 @default.
- W2068619783 hasAuthorship W2068619783A5066995769 @default.
- W2068619783 hasAuthorship W2068619783A5073119979 @default.
- W2068619783 hasAuthorship W2068619783A5090276194 @default.
- W2068619783 hasConcept C104317684 @default.
- W2068619783 hasConcept C122927707 @default.
- W2068619783 hasConcept C136229726 @default.
- W2068619783 hasConcept C148738053 @default.
- W2068619783 hasConcept C171089720 @default.
- W2068619783 hasConcept C175369904 @default.
- W2068619783 hasConcept C185592680 @default.
- W2068619783 hasConcept C198826908 @default.
- W2068619783 hasConcept C201750760 @default.
- W2068619783 hasConcept C202751555 @default.
- W2068619783 hasConcept C203014093 @default.
- W2068619783 hasConcept C2776175234 @default.
- W2068619783 hasConcept C2780007613 @default.
- W2068619783 hasConcept C28328180 @default.
- W2068619783 hasConcept C54355233 @default.
- W2068619783 hasConcept C55493867 @default.
- W2068619783 hasConcept C71924100 @default.
- W2068619783 hasConcept C81885089 @default.
- W2068619783 hasConcept C86803240 @default.