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• W2068630007 abstract "Last year we published 2 articles listing and describing the Red Journal's most downloaded articles of 2011 (1Zietman A. The Red Journal's top 10 most downloaded articles of 2011.Int J Radiat Oncol Biol Phys. 2012; 83: 1073-1074Abstract Full Text Full Text PDF PubMed Scopus (9) Google Scholar, 2Zietman A. Top 10 clinical research downloads of 2011.Int J Radiat Oncol Biol Phys. 2012; 4: 869-870Abstract Full Text Full Text PDF Scopus (8) Google Scholar). They proved very popular and, by a strange irony, one of them became itself one of our most downloaded articles! This year, I have elected to look back at 2012 and do the same but with some further categorization. In reading these lists, I am struck, as I think you will be also, by the evolution of clinicians' interests over recent years. These are by far the most downloaded articles at present. They cover everyday problems in common clinical scenarios and represent the best efforts of a broad spectrum of experts to reach agreement. These articles keep practicing clinicians safe, they keep patients safe, and they keep malpractice lawyers at bay. As radiation oncology transforms to a highly technical imaging-based practice, the need to learn techniques that were, in many cases, not taught during training becomes urgent. Defining target volumes using magnetic resonance imaging (MRI) and computed tomography (CT) is one such technique, in addition to contouring anatomically complex normal structures, such as the brachial plexus (3Hall W.H. Guiou M. Lee N.Y. et al.Development and validation of a standardized method for contouring the brachial plexus: preliminary dosimetric analysis among patients treated with IMRT for head-and-neck cancer.Int J Radiat Oncol Biol Phys. 2008; 72: 1362-1367Abstract Full Text Full Text PDF PubMed Scopus (98) Google Scholar, 4Kong F.M. Ritter T. Quint D.J. et al.Consideration of dose limits for organs at risk of thoracic radiotherapy: atlas for lung, proximal bronchial tree, esophagus, spinal cord, ribs, and brachial plexus.Int J Radiat Oncol Biol Phys. 2011; 81: 1442-1457Abstract Full Text Full Text PDF PubMed Scopus (219) Google Scholar). However, as some aspects of our scope of practice change dramatically, others change not at all, and the American Society for Radiation Oncology (ASTRO) evidence-based guidelines for the palliative management of bone metastases proved essential reading (5Lutz S. Berk L. Chang E. et al.Palliative radiotherapy for bone metastases: an ASTRO evidence-based guideline.Int J Radiat Oncol Biol Phys. 2011; 79: 965-976Abstract Full Text Full Text PDF PubMed Scopus (632) Google Scholar) (Table 1).Table 1Top 10 most downloaded articlesRankArticle (ref)1Hall WH et al, 2008. Development and Validation of a Standardized Method for Contouring the Brachial Plexus: Preliminary Dosimetric Analysis Among Patients Treated With IMRT for Head-and-Neck Cancer 3Hall W.H. Guiou M. Lee N.Y. et al.Development and validation of a standardized method for contouring the brachial plexus: preliminary dosimetric analysis among patients treated with IMRT for head-and-neck cancer.Int J Radiat Oncol Biol Phys. 2008; 72: 1362-1367Abstract Full Text Full Text PDF PubMed Scopus (98) Google Scholar2Gay HA et al, 2012. Pelvic Normal Tissue Contouring Guidelines for Radiation Therapy: A Radiation Therapy Oncology Group Consensus Panel Atlas 6Gay H.A. Barthold H.J. O'Meara E. et al.Pelvic normal tissue contouring guidelines for radiation therapy: a Radiation Therapy Oncology Group consensus panel atlas.Int J Radiat Oncol Biol Phys. 2012; 83: e353-e362Abstract Full Text Full Text PDF PubMed Scopus (317) Google Scholar3Marks LB et al, 2010. Use of Normal Tissue Complication Probability Models in the Clinic 7Marks L.B. Yorke E.D. Jackson A. et al.Use of normal tissue complication probability models in the clinic.Int J Radiat Oncol Biol Phys. 2010; 75: S10-S19Abstract Full Text Full Text PDF Scopus (1045) Google Scholar4Lim K et al, 2011. Consensus Guidelines for Delineation of Clinical Target Volume for Intensity-Modulated Pelvic Radiotherapy for the Definitive Treatment of Cervix Cancer 8Lim K. Small Jr., W. Portlance L. et al.Consensus guidelines for delineation of clinical target volume for intensity-modulated pelvic radiotherapy for the definitive treatment of cervix cancer.Int J Radiat Oncol Biol Phys. 2011; 79: 348-355Abstract Full Text Full Text PDF PubMed Scopus (285) Google Scholar5Kong FM et al, 2011. Consideration of Dose Limits for Organs at Risk of Thoracic Radiotherapy: Atlas for Lung, Proximal Bronchial Tree, Esophagus, Spinal Cord, Ribs, and Brachial Plexus 4Kong F.M. Ritter T. Quint D.J. et al.Consideration of dose limits for organs at risk of thoracic radiotherapy: atlas for lung, proximal bronchial tree, esophagus, spinal cord, ribs, and brachial plexus.Int J Radiat Oncol Biol Phys. 2011; 81: 1442-1457Abstract Full Text Full Text PDF PubMed Scopus (219) Google Scholar6Lutz S et al, 2011. Palliative Radiotherapy for Bone Metastases: An ASTRO Evidence-Based Guideline 5Lutz S. Berk L. Chang E. et al.Palliative radiotherapy for bone metastases: an ASTRO evidence-based guideline.Int J Radiat Oncol Biol Phys. 2011; 79: 965-976Abstract Full Text Full Text PDF PubMed Scopus (632) Google Scholar7Goodman KA et al, 2012. Radiation Therapy Oncology Group Consensus Panel Guidelines for the Delineation of the Clinical Target Volume in the Postoperative Treatment of Pancreatic Head Cancer 9Goodman K.A. Regine W.F. Dawson L.A. et al.Radiation Therapy Oncology Group consensus panel guidelines for the delineation of the clinical target volume in the postoperative treatment of pancreatic head cancer.Int J Radiat Oncol Biol Phys. 2012; 83: 901-908Abstract Full Text Full Text PDF PubMed Scopus (86) Google Scholar8Myerson RJ et al, 2009. Elective Clinical Target Volumes for Conformal Therapy in Anorectal Cancer: A Radiation Therapy Oncology Group Consensus Panel Contouring Atlas 10Myerson R.J. Garofalo M.C. El Naqa I. et al.Elective clinical target volumes for conformal therapy in anorectal cancer: a radiation therapy oncology group consensus panel contouring atlas.Int J Radiat Oncol Biol Phys. 2009; 74: 824-830Abstract Full Text Full Text PDF PubMed Scopus (339) Google Scholar9Huguet F et al, 2012. Radiotherapy Technical Considerations in the Management of Locally Advanced Pancreatic Cancer: American-French Consensus Recommendations 11Huguet F. Goodman K.A. Azria D. et al.Radiotherapy technical considerations in the management of locally advanced pancreatic cancer: American-French consensus recommendations.Int J Radiat Oncol Biol Phys. 2012; 83: 1355-1364Abstract Full Text Full Text PDF PubMed Scopus (55) Google Scholar10Small W Jr. et al, 2008. Consensus Guidelines for Delineation of Clinical Target Volume for Intensity-Modulated Pelvic Radiotherapy in Postoperative Treatment of Endometrial and Cervical Cancer 12Small Jr., W. Mell L.K. Anderson P. et al.Consensus guidelines for delineation of clinical target volume for intensity-modulated pelvic radiotherapy in postoperative treatment of endometrial and cervical cancer.Int J Radiat Oncol Biol Phys. 2008; 71: 428-434Abstract Full Text Full Text PDF PubMed Scopus (288) Google Scholar Open table in a new tab These are original research articles, and one can clearly see the power and credibility of randomized control trials. Two such studies with long-term outcomes proved influential and popular. In addition, 2 large series looking at stereotactic body radiation therapy (SBRT) reflect the huge expansion of interest in this modality over recent years (13Onishi H. Shirato H. Nagata Y. et al.Stereotactic body radiotherapy (SBRT) for operable stage I non-small-cell lung cancer: can SBRT be comparable to surgery?.Int J Radiat Oncol Biol Phys. 2011; 81: 1352-1358Abstract Full Text Full Text PDF PubMed Scopus (466) Google Scholar, 14King C.R. Brooks J.D. Gill H. et al.Long-term outcomes from a prospective trial of stereotactic body radiotherapy for low-risk prostate cancer.Int J Radiat Oncol Biol Phys. 2012; 82: 877-882Abstract Full Text Full Text PDF PubMed Scopus (296) Google Scholar). Several of the top 10 original articles looked at the use of SBRT in non-small cell lung cancer patients in a number of different scenarios (15Palma D. Lagerwaard F. Rodrigues G. et al.Curative treatment of stage I non-small-cell lung cancer in patients with severe COPD: stereotactic radiotherapy outcomes and systematic review.Int J Radiat Oncol Biol Phys. 2012; 82: 1149-1156Abstract Full Text Full Text PDF PubMed Scopus (141) Google Scholar). Milano et al (16Milano M.T. Katz A.W. Zhang H. et al.Oligometastases treated with stereotactic body radiotherapy: long-term follow-up of prospective study.Int J Radiat Oncol Biol Phys. 2012; 83: 878-886Abstract Full Text Full Text PDF PubMed Scopus (332) Google Scholar) studied the expanding concept of oligo-metastatic disease where SBRT has a major role. Randomized trials are always well regarded and well read, contributing to the high volume of downloads for the long-term results of PORTEC and Radiation Therapy Oncology Group (RTOG) trials (17Creutzberg C.L. Nout R.A. Lybeert M.L. et al.Fifteen-year radiotherapy outcomes of the randomized PORTEC-1 trial for endometrial carcinoma.Int J Radiat Oncol Biol Phys. 2011; 81: e631-e638Abstract Full Text Full Text PDF PubMed Scopus (212) Google Scholar, 18Yi S.K. Hall W.H. Mathai M. et al.Validating the RTOG-endorsed brachial plexus contouring atlas: an evaluation of reproducibility among patients treated by intensity-modulated radiotherapy for head-and-neck cancer.Int J Radiat Oncol Biol Phys. 2012; 82: 1060-1064Abstract Full Text Full Text PDF PubMed Scopus (22) Google Scholar, 19Cooper J.S. Zhang Q. Pajak T.F. et al.Long-term follow-up of the RTOG 9501/intergroup phase III trial: postoperative concurrent radiation therapy and chemotherapy in high-risk squamous cell carcinoma of the head and neck.Int J Radiat Oncol Biol Phys. 2012; 84: 1198-1205Abstract Full Text Full Text PDF PubMed Scopus (311) Google Scholar), as well as the role of bevacizumab in preventing brain necrosis feature (20Levin V.A. Bidaut L. Hou P. et al.Randomized double-blind placebo-controlled trial of bevacizumab therapy for radiation necrosis of the central nervous system.Int J Radiat Oncol Biol Phys. 2011; 79: 1487-1495Abstract Full Text Full Text PDF PubMed Scopus (477) Google Scholar) (Table 2).Table 2Top 10 clinical science downloadsRankArticle (ref)1Creutzberg CL et al, 2011. Fifteen-Year Radiotherapy Outcomes of the Randomized PORTEC-1 Trial for Endometrial Carcinoma 17Creutzberg C.L. Nout R.A. Lybeert M.L. et al.Fifteen-year radiotherapy outcomes of the randomized PORTEC-1 trial for endometrial carcinoma.Int J Radiat Oncol Biol Phys. 2011; 81: e631-e638Abstract Full Text Full Text PDF PubMed Scopus (212) Google Scholar2Yi SK et al, 2012. Validating the RTOG-Endorsed Brachial Plexus Contouring Atlas: An Evaluation of Reproducibility Among Patients Treated by Intensity-Modulated Radiotherapy for Head-and-Neck Cancer 18Yi S.K. Hall W.H. Mathai M. et al.Validating the RTOG-endorsed brachial plexus contouring atlas: an evaluation of reproducibility among patients treated by intensity-modulated radiotherapy for head-and-neck cancer.Int J Radiat Oncol Biol Phys. 2012; 82: 1060-1064Abstract Full Text Full Text PDF PubMed Scopus (22) Google Scholar3Milano MT et al, 2012. Oligometastases Treated With Stereotactic Body Radiotherapy: Long-Term Follow-Up of Prospective Study 16Milano M.T. Katz A.W. Zhang H. et al.Oligometastases treated with stereotactic body radiotherapy: long-term follow-up of prospective study.Int J Radiat Oncol Biol Phys. 2012; 83: 878-886Abstract Full Text Full Text PDF PubMed Scopus (332) Google Scholar4Palma D et al, 2012. Curative Treatment of Stage I Non-Small-Cell Lung Cancer in Patients With Severe COPD: Stereotactic Radiotherapy Outcomes and Systematic Review 15Palma D. Lagerwaard F. Rodrigues G. et al.Curative treatment of stage I non-small-cell lung cancer in patients with severe COPD: stereotactic radiotherapy outcomes and systematic review.Int J Radiat Oncol Biol Phys. 2012; 82: 1149-1156Abstract Full Text Full Text PDF PubMed Scopus (141) Google Scholar5Cooper JS et al, 2012. Long-term Follow-up of the RTOG 9501/Intergroup Phase III Trial: Postoperative Concurrent Radiation Therapy and Chemotherapy in High-Risk Squamous Cell Carcinoma of the Head and Neck 19Cooper J.S. Zhang Q. Pajak T.F. et al.Long-term follow-up of the RTOG 9501/intergroup phase III trial: postoperative concurrent radiation therapy and chemotherapy in high-risk squamous cell carcinoma of the head and neck.Int J Radiat Oncol Biol Phys. 2012; 84: 1198-1205Abstract Full Text Full Text PDF PubMed Scopus (311) Google Scholar6Onishi H et al, 2011. Stereotactic Body Radiotherapy (SBRT) for Operable Stage I Non-Small-Cell Lung Cancer: Can SBRT Be Comparable to Surgery? 13Onishi H. Shirato H. Nagata Y. et al.Stereotactic body radiotherapy (SBRT) for operable stage I non-small-cell lung cancer: can SBRT be comparable to surgery?.Int J Radiat Oncol Biol Phys. 2011; 81: 1352-1358Abstract Full Text Full Text PDF PubMed Scopus (466) Google Scholar7Zelefsky MJ et al, 2012. Improved Clinical Outcomes With High-Dose Image Guided Radiotherapy Compared With Non-IGRT for the Treatment of Clinically Localized Prostate Cancer 21Zelefsky M.J. Kollmeier M. Cox B. et al.Improved clinical outcomes with high-dose image guided radiotherapy compared with non-IGRT for the treatment of clinically localized prostate cancer.Int J Radiat Oncol Biol Phys. 2012; 84: 125-129Abstract Full Text Full Text PDF PubMed Scopus (372) Google Scholar8King CR et al, 2012. Long-Term Outcomes From a Prospective Trial of Stereotactic Body Radiotherapy for Low-Risk Prostate Cancer 14King C.R. Brooks J.D. Gill H. et al.Long-term outcomes from a prospective trial of stereotactic body radiotherapy for low-risk prostate cancer.Int J Radiat Oncol Biol Phys. 2012; 82: 877-882Abstract Full Text Full Text PDF PubMed Scopus (296) Google Scholar9Levin VA et al, 2011. Randomized Double-Blind Placebo-Controlled Trial of Bevacizumab Therapy for Radiation Necrosis of the Central Nervous System 20Levin V.A. Bidaut L. Hou P. et al.Randomized double-blind placebo-controlled trial of bevacizumab therapy for radiation necrosis of the central nervous system.Int J Radiat Oncol Biol Phys. 2011; 79: 1487-1495Abstract Full Text Full Text PDF PubMed Scopus (477) Google Scholar10Tendulkar RD et al, 2012. Impact of Postmastectomy Radiation on Locoregional Recurrence in Breast Cancer Patients With 1-3 Positive Lymph Nodes Treated With Modern Systemic Therapy 22Tendulkar R.D. Rehman S. Shukla M.E. et al.Impact of postmastectomy radiation on locoregional recurrence in breast cancer patients with 1-3 positive lymph nodes treated with modern systemic therapy.Int J Radiat Oncol Biol Phys. 2012; 83: e577-e581Abstract Full Text Full Text PDF PubMed Scopus (77) Google Scholar Open table in a new tab These articles represent a helpful and convenient synthesis of disparate studies in a field of interest. Their popularity reflects, first, the relevance of the subject matter and, second, the fact that they are often accompanied by continuing medical education (CME) credit. In this age of continuous assessment by the American Board of Radiology, reading a review and completing self-testing is an inexpensive and highly practical way for specialists to keep up. A burgeoning area of interest for radiation oncologists is reflected in the top downloaded review, covering the treatment of liver metastases, an area in which the specialty previously had only a limited role but that is now growing explosively (23Høyer M. Swaminath A. Bydder S. et al.Radiotherapy for liver metastases: a review of evidence.Int J Radiat Oncol Biol Phys. 2012; 82: 1047-1057Abstract Full Text Full Text PDF PubMed Scopus (155) Google Scholar). Interestingly, the article by Herbst (24Herbst R.S. Review of epidermal growth factor receptor biology.Int J Radiat Oncol Biol Phys. 2004; 59: 21-26Abstract Full Text Full Text PDF PubMed Scopus (979) Google Scholar) on epidermal growth factor receptor (EGFR) remains popular despite being written in 2004. This review provides a solid foundation for a molecular target of growing importance in the world of oncology. A new review by Ausborn et al (25Ausborn N.L. Le Q.T. Bradley J.D. et al.Molecular profiling to optimize treatment in non-small-cell lung cancer: a review of potential molecular targets for radiation therapy by the translational research program of the Radiation Therapy Oncology Group.Int J Radiat Oncol Biol Phys. 2012; 83: e453-e464Abstract Full Text Full Text PDF PubMed Scopus (33) Google Scholar) on molecular targets of interest for radiation therapy in patients with non-small cell lung cancer emphasizes the desire of radiation oncologists to engage with and understand this new world. The review by Loblaw et al (26Loblaw D.A. Mitera G. Ford M. et al.A 2011 updated systematic review and clinical practice guideline for the management of malignant extradural spinal cord compression.Int J Radiat Oncol Biol Phys. 2012; 84: 312-317Abstract Full Text Full Text PDF PubMed Scopus (99) Google Scholar) on the perennial problem of spinal cord compression by extradural metastases was, unsurprisingly, frequently read. Also well read were reviews of papers on pancreatic cancer (27Johung K. Saif M.W. Chang B.W. Treatment of locally advanced pancreatic cancer: the role of radiation therapy.Int J Radiat Oncol Biol Phys. 2012; 82: 508-518Abstract Full Text Full Text PDF PubMed Scopus (34) Google Scholar), seminoma target volumes (28Wilder R.B. Buyyounouski M.K. Efstathiou J.A. et al.Radiotherapy treatment planning for testicular seminoma.Int J Radiat Oncol Biol Phys. 2012; 83: e445-e452Abstract Full Text Full Text PDF PubMed Scopus (22) Google Scholar), sarcomas (29Haas R.L. Delaney T.F. O'Sullivan B. et al.Radiotherapy for management of extremity soft tissue sarcomas: why, when, and where?.Int J Radiat Oncol Biol Phys. 2012; 84: 572-580Abstract Full Text Full Text PDF PubMed Scopus (134) Google Scholar), and the reirradiation of bone metastases (30Huisman M. van den Bosch M.A. Wijlemans J.W. et al.Effectiveness of reirradiation for painful bone metastases: a systematic review and meta-analysis.Int J Radiat Oncol Biol Phys. 2012; 84: 8-14Abstract Full Text Full Text PDF PubMed Scopus (115) Google Scholar) (Table 3).Table 3Top 10 review articlesRankArticle (ref)1Høyer M et al, 2012. Radiotherapy for Liver Metastases: A Review of Evidence 23Høyer M. Swaminath A. Bydder S. et al.Radiotherapy for liver metastases: a review of evidence.Int J Radiat Oncol Biol Phys. 2012; 82: 1047-1057Abstract Full Text Full Text PDF PubMed Scopus (155) Google Scholar2Herbst RS et al, 2004. Review of Epidermal Growth Factor Receptor Biology 24Herbst R.S. Review of epidermal growth factor receptor biology.Int J Radiat Oncol Biol Phys. 2004; 59: 21-26Abstract Full Text Full Text PDF PubMed Scopus (979) Google Scholar3Loblaw DA et al, 2012. A 2011 Updated Systematic Review and Clinical Practice Guideline for the Management of Malignant Extradural Spinal Cord Compression 26Loblaw D.A. Mitera G. Ford M. et al.A 2011 updated systematic review and clinical practice guideline for the management of malignant extradural spinal cord compression.Int J Radiat Oncol Biol Phys. 2012; 84: 312-317Abstract Full Text Full Text PDF PubMed Scopus (99) Google Scholar4Johung K et al, 2012. Treatment of Locally Advanced Pancreatic Cancer: The Role of Radiation Therapy 27Johung K. Saif M.W. Chang B.W. Treatment of locally advanced pancreatic cancer: the role of radiation therapy.Int J Radiat Oncol Biol Phys. 2012; 82: 508-518Abstract Full Text Full Text PDF PubMed Scopus (34) Google Scholar5Ausborn NL et al, 2012. Molecular Profiling to Optimize Treatment in Non-Small Cell Lung Cancer: A Review of Potential Molecular Targets for Radiation Therapy by the Translational Research Program of the Radiation Therapy Oncology Group 25Ausborn N.L. Le Q.T. Bradley J.D. et al.Molecular profiling to optimize treatment in non-small-cell lung cancer: a review of potential molecular targets for radiation therapy by the translational research program of the Radiation Therapy Oncology Group.Int J Radiat Oncol Biol Phys. 2012; 83: e453-e464Abstract Full Text Full Text PDF PubMed Scopus (33) Google Scholar6Wilder B et al, 2012. Radiotherapy Treatment Planning for Testicular Seminoma 28Wilder R.B. Buyyounouski M.K. Efstathiou J.A. et al.Radiotherapy treatment planning for testicular seminoma.Int J Radiat Oncol Biol Phys. 2012; 83: e445-e452Abstract Full Text Full Text PDF PubMed Scopus (22) Google Scholar7Haas RL et al, 2012. Radiotherapy for Management of Extremity Soft Tissue Sarcomas: Why, When, and Where? 29Haas R.L. Delaney T.F. O'Sullivan B. et al.Radiotherapy for management of extremity soft tissue sarcomas: why, when, and where?.Int J Radiat Oncol Biol Phys. 2012; 84: 572-580Abstract Full Text Full Text PDF PubMed Scopus (134) Google Scholar8Shah C et al, 2011. Breast Cancer-Related Arm Lymphedema: Incidence Rates, Diagnostic Techniques, Optimal Management and Risk Reduction Strategies 31Shah C. Vicini F.A. Breast cancer-related arm lymphedema: incidence rates, diagnostic techniques, optimal management and risk reduction strategies.Int J Radiat Oncol Biol Phys. 2011; 81: 907-914Abstract Full Text Full Text PDF PubMed Scopus (113) Google Scholar9Huisman M et al, 2012. Effectiveness of Reirradiation for Painful Bone Metastases: A Systematic Review and Meta-Analysis 30Huisman M. van den Bosch M.A. Wijlemans J.W. et al.Effectiveness of reirradiation for painful bone metastases: a systematic review and meta-analysis.Int J Radiat Oncol Biol Phys. 2012; 84: 8-14Abstract Full Text Full Text PDF PubMed Scopus (115) Google Scholar10Fowble BL et al, 2012. Role of Postmastectomy Radiation After Neoadjuvant Chemotherapy in Stage II-III Breast Cancer 32Fowble B.L. Einck J.P. Kim D.N. et al.Role of postmastectomy radiation after neoadjuvant chemotherapy in stage II-III breast cancer.Int J Radiat Oncol Biol Phys. 2012; 83: 494-503PubMed Scopus (70) Google Scholar Open table in a new tab The top 4 editorial and special articles of 2012 were quite diverse and reflect a range of contemporary concerns. Drs Cox (33Cox J.D. Are the results of RTOG 0617 nysterious?.Int J Radiat Oncol Biol Phys. 2012; 82: 1042-1044Abstract Full Text Full Text PDF PubMed Scopus (102) Google Scholar) and King (34King C.R. Adjuvant versus salvage radiotherapy after prostatectomy: the apple versus the orange.Int J Radiat Oncol Biol Phys. 2012; 82: 1045-1046Abstract Full Text Full Text PDF PubMed Scopus (12) Google Scholar) tried to make sense of randomized data, repackaging it more neatly for our interpretation. Cox reviewed RTOG protocol 0617, studying the integration of cetuximab with chemoradiation in non-small cell lung cancer patients, and King took a big overview of the debate regarding adjuvant and salvage radiation after prostatectomy. The Red Journal's first retraction in many years was also of considerable interest (35Avilés A. Neri N. Fernández R. et al.RETRACTED: randomized clinical trial to assess the efficacy of radiotherapy in primary mediastinal large B-lymphoma.Int J Radiat Oncol Biol Phys. 2012; 83: 1227-1231Abstract Full Text PDF PubMed Scopus (10) Google Scholar). Upholding the journal's scientific integrity is a major concern of the editorial team, and over the past few months, we have had to retract 2 published papers because of problems with the analysis that could not be simply resolved by reanalysis and an erratum. We do not regard these retractions as a “badge of shame,” either for the journal or, in this case, the authors but instead feel that they demonstrate convincingly that we do not brush scientific concerns under the rug (Table 4).Table 4Top 4 editorials and special articlesRankArticle (ref)1Cox JD, 2012. Are the Results of RTOG 0617 Mysterious? 33Cox J.D. Are the results of RTOG 0617 nysterious?.Int J Radiat Oncol Biol Phys. 2012; 82: 1042-1044Abstract Full Text Full Text PDF PubMed Scopus (102) Google Scholar2King CR, 2012. Adjuvant Versus Salvage Radiotherapy After Prostatectomy: The Apple Versus the Orange 34King C.R. Adjuvant versus salvage radiotherapy after prostatectomy: the apple versus the orange.Int J Radiat Oncol Biol Phys. 2012; 82: 1045-1046Abstract Full Text Full Text PDF PubMed Scopus (12) Google Scholar3Avilés A et al, 2012. RETRACTED: Randomized Clinical Trial to Assess the Efficacy of Radiotherapy in Primary Mediastinal Large B-Lymphoma 35Avilés A. Neri N. Fernández R. et al.RETRACTED: randomized clinical trial to assess the efficacy of radiotherapy in primary mediastinal large B-lymphoma.Int J Radiat Oncol Biol Phys. 2012; 83: 1227-1231Abstract Full Text PDF PubMed Scopus (10) Google Scholar4Zietman A, 2012. The Red Journal's Top 10 Most Downloaded Articles of 2011 1Zietman A. The Red Journal's top 10 most downloaded articles of 2011.Int J Radiat Oncol Biol Phys. 2012; 83: 1073-1074Abstract Full Text Full Text PDF PubMed Scopus (9) Google Scholar Open table in a new tab" @default.
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