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• W2068668529 abstract "The aim of the study is to investigate the effect of recombinant Ganoderma lucidum immunoregulatory protein (rLZ-8) on mouse models of cyclophosphamide-induced leukopenia, which we have established with both single-phase and multi-phase administration methods. Treatment with rLZ-8 had a strong effect on both models of cyclophosphamide-induced leukopenia. In particular, it increased the number of neutrophils, lymphocytes and monocytes. rLZ-8 treatment also increased the percentage of CD4(+) T cells and the levels of secreted IL-3 and IL-4, which contributed to the cyclophosphamide-induced immune dysfunction and immune system imbalance. In conclusion, rLZ-8 treatment benefitted mice with cyclophosphamide-induced leukopenia by improving overall immune function and by specifically increasing the number of white blood cells." @default.
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• W2068668529 date "2013-05-08" @default.
• W2068668529 modified "2023-10-14" @default.
• W2068668529 title "Effect of recombinant<i>Ganoderma lucidum</i>immunoregulatory protein on cyclophosphamide-induced leukopenia in mice" @default.
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• W2068668529 doi "https://doi.org/10.3109/08923973.2013.791834" @default.
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