FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W206867187> ?p ?o ?g. }

• W206867187 endingPage "1479" @default.
• W206867187 startingPage "1456" @default.
• W206867187 abstract "In the previous paper we have demonstrated, by means of field potential and extracellular unit recordings, that bicuculline-induced seizures, which include spike-wave (SW) or polyspike-wave (PSW) complexes, are initiated intracortically and survive ipsilateral thalamectomy. Here, we used multisite field potential and extracellular recordings to validate the patterns of cortical SW/PSW seizures in chronically implanted, behaving cats. To investigate the cellular patterns and excitability during spontaneously occurring and electrically elicited cortical seizures, we used single and dual intracellular recordings from regular-spiking (RS) and fast-rhythmic-bursting (FRB) cortical neurons, in conjunction with field potential recordings from neocortex and related thalamic nuclei, in cats maintained under ketamine-xylazine anesthesia. 1) Invariably, the spontaneous or electrically induced seizures were initiated within the cortex of both behaving and anesthetized animals. Spontaneously occurring, compound seizures consisting of SW/PSW complexes at 2-4 Hz and fast runs at 10-15 Hz, developed without discontinuity from the slow (mainly 0.5-0.9 Hz), sleeplike, cortically generated oscillation. 2) During SW/PSW complexes, RS neurons discharged spike trains during the depth-negative component of the cortical spike component of field potentials and were hyperpolarized during the depth-positive field wave. The FRB neurons fired many more action potentials than RS cells during SW/PSW complexes. Averaged activities triggered by the spiky field potentials or by the steepest slope of depolarization in cortical neurons demonstrated similar relations between intracellular activities and field potentials during sleep and seizure epochs, the latter-being an exaggeration of the depolarizing and hyperpolarizing components of the slow sleep oscillation. 3) During the fast runs, RS cells were tonically depolarized and discharged single action potentials or spike doublets (usually with pronounced spike inactivation), whereas FRB cells discharged rhythmic spike bursts, time locked with the depth-negative field potentials. 4) Neuronal excitability, tested by depolarizing current pulses applied throughout the seizures and compared with pre- and postseizure epochs, showed a decreased number of evoked action potentials during both seizure components (SW/PSW complexes and fast runs), eventually leading to null responses during the postictal depression. 5) Data suggest that interconnected FRB neurons may play an important role in the initiation of cortical seizures. We discuss the similarities between the electrographic patterns described in this study and those found in different forms of clinical seizures." @default.
• W206867187 created "2016-06-24" @default.
• W206867187 creator A5027974197 @default.
• W206867187 creator A5052410173 @default.
• W206867187 creator A5071552648 @default.
• W206867187 creator A5076117266 @default.
• W206867187 date "1998-09-01" @default.
• W206867187 modified "2023-10-18" @default.
• W206867187 title "Spike-Wave Complexes and Fast Components of Cortically Generated Seizures. II. Extra- and Intracellular Patterns" @default.
• W206867187 cites W1533320261 @default.
• W206867187 cites W1540311052 @default.
• W206867187 cites W1608961846 @default.
• W206867187 cites W1676571406 @default.
• W206867187 cites W1679402667 @default.
• W206867187 cites W1840565448 @default.
• W206867187 cites W1852080917 @default.
• W206867187 cites W1855116957 @default.
• W206867187 cites W1856661504 @default.
• W206867187 cites W1877020112 @default.
• W206867187 cites W1944684909 @default.
• W206867187 cites W1963617392 @default.
• W206867187 cites W1973050784 @default.
• W206867187 cites W1984539951 @default.
• W206867187 cites W1993506942 @default.
• W206867187 cites W1997596070 @default.
• W206867187 cites W1998620428 @default.
• W206867187 cites W2001150734 @default.
• W206867187 cites W2007639691 @default.
• W206867187 cites W2011318716 @default.
• W206867187 cites W2015468513 @default.
• W206867187 cites W2020272049 @default.
• W206867187 cites W2022890204 @default.
• W206867187 cites W2026026408 @default.
• W206867187 cites W2028848906 @default.
• W206867187 cites W2030670571 @default.
• W206867187 cites W2031592435 @default.
• W206867187 cites W2038879792 @default.
• W206867187 cites W2039792054 @default.
• W206867187 cites W2041343218 @default.
• W206867187 cites W2046717384 @default.
• W206867187 cites W2047750300 @default.
• W206867187 cites W2050215995 @default.
• W206867187 cites W2055397614 @default.
• W206867187 cites W2057081970 @default.
• W206867187 cites W2059474422 @default.
• W206867187 cites W2062984127 @default.
• W206867187 cites W2064392570 @default.
• W206867187 cites W2066521805 @default.
• W206867187 cites W2073191776 @default.
• W206867187 cites W2074780489 @default.
• W206867187 cites W2076013083 @default.
• W206867187 cites W2094167907 @default.
• W206867187 cites W2094677905 @default.
• W206867187 cites W2096519870 @default.
• W206867187 cites W2123831735 @default.
• W206867187 cites W2131307957 @default.
• W206867187 cites W2137231621 @default.
• W206867187 cites W2146288322 @default.
• W206867187 cites W2146751262 @default.
• W206867187 cites W2165145371 @default.
• W206867187 cites W2171255353 @default.
• W206867187 cites W2259404637 @default.
• W206867187 cites W2270999310 @default.
• W206867187 cites W2291836720 @default.
• W206867187 cites W2324671611 @default.
• W206867187 cites W2342621347 @default.
• W206867187 cites W2407457223 @default.
• W206867187 cites W2776211375 @default.
• W206867187 cites W4295831928 @default.
• W206867187 doi "https://doi.org/10.1152/jn.1998.80.3.1456" @default.
• W206867187 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9744952" @default.
• W206867187 hasPublicationYear "1998" @default.
• W206867187 type Work @default.
• W206867187 sameAs 206867187 @default.
• W206867187 citedByCount "180" @default.
• W206867187 countsByYear W2068671872012 @default.
• W206867187 countsByYear W2068671872013 @default.
• W206867187 countsByYear W2068671872014 @default.
• W206867187 countsByYear W2068671872015 @default.
• W206867187 countsByYear W2068671872016 @default.
• W206867187 countsByYear W2068671872017 @default.
• W206867187 countsByYear W2068671872018 @default.
• W206867187 countsByYear W2068671872019 @default.
• W206867187 countsByYear W2068671872020 @default.
• W206867187 countsByYear W2068671872021 @default.
• W206867187 countsByYear W2068671872022 @default.
• W206867187 countsByYear W2068671872023 @default.
• W206867187 crossrefType "journal-article" @default.
• W206867187 hasAuthorship W206867187A5027974197 @default.
• W206867187 hasAuthorship W206867187A5052410173 @default.
• W206867187 hasAuthorship W206867187A5071552648 @default.
• W206867187 hasAuthorship W206867187A5076117266 @default.
• W206867187 hasConcept C117838684 @default.
• W206867187 hasConcept C120416640 @default.
• W206867187 hasConcept C12554922 @default.
• W206867187 hasConcept C126322002 @default.
• W206867187 hasConcept C168258287 @default.
• W206867187 hasConcept C169760540 @default.

• next