Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068697570> ?p ?o ?g. }
- W2068697570 endingPage "5047" @default.
- W2068697570 startingPage "5036" @default.
- W2068697570 abstract "In situ remineralization of hydroxyapatite (HA) on human tooth enamel surface induced by organic matrices is of great interest in the fields of material science and stomatology. In order to mimic the organic matrices induced biomineralization process in developing enamel and enhance the binding strength at the remineralization interface, carboxyl-terminated poly(amido amine) (PAMAM-COOH)-alendronate (ALN) conjugate (ALN-PAMAM-COOH) was synthesized and characterized. PAMAM-COOH has a highly ordered architecture and is capable of promoting the HA crystallization process. ALN is conjugated on PAMAM-COOH due to its specific adsorption on HA (the main component of tooth enamel), resulting in increased binding strength which is tight enough to resist phosphate buffered saline (PBS) rinsing as compared with that of PAMAM-COOH alone. While incubated in artificial saliva, ALN-PAMAM-COOH could induce in situ remineralization of HA on acid-etched enamel, and the regenerated HA has the nanorod-like crystal structure similar to that of human tooth enamel. The hardness of acid-etched enamel samples treated by ALN-PAMAM-COOH can recover up to 95.5% of the original value with strong adhesion force. In vivo experiment also demonstrates that ALN-PAMAM-COOH is effective in repairing acid-etched enamel in the oral cavity. Overall, these results suggest that ALN-PAMAM-COOH is highly promising as a restorative biomaterial for in situ remineralization of human tooth enamel." @default.
- W2068697570 created "2016-06-24" @default.
- W2068697570 creator A5001553975 @default.
- W2068697570 creator A5003048399 @default.
- W2068697570 creator A5011487190 @default.
- W2068697570 creator A5011866398 @default.
- W2068697570 creator A5043296871 @default.
- W2068697570 creator A5044038805 @default.
- W2068697570 creator A5049025559 @default.
- W2068697570 creator A5058333725 @default.
- W2068697570 date "2013-07-01" @default.
- W2068697570 modified "2023-10-14" @default.
- W2068697570 title "Hydroxyapatite-anchored dendrimer for in situ remineralization of human tooth enamel" @default.
- W2068697570 cites W1960290552 @default.
- W2068697570 cites W1965633792 @default.
- W2068697570 cites W1967637692 @default.
- W2068697570 cites W1980755856 @default.
- W2068697570 cites W1982100351 @default.
- W2068697570 cites W1983215048 @default.
- W2068697570 cites W1991600810 @default.
- W2068697570 cites W1992212956 @default.
- W2068697570 cites W1994298655 @default.
- W2068697570 cites W2000283697 @default.
- W2068697570 cites W2003628031 @default.
- W2068697570 cites W2004228065 @default.
- W2068697570 cites W2006682004 @default.
- W2068697570 cites W2009500363 @default.
- W2068697570 cites W2024988429 @default.
- W2068697570 cites W2025756438 @default.
- W2068697570 cites W2036181729 @default.
- W2068697570 cites W2041636695 @default.
- W2068697570 cites W2045123944 @default.
- W2068697570 cites W2045631815 @default.
- W2068697570 cites W2046911609 @default.
- W2068697570 cites W2051662131 @default.
- W2068697570 cites W2055523859 @default.
- W2068697570 cites W2057650100 @default.
- W2068697570 cites W2059791081 @default.
- W2068697570 cites W2061923475 @default.
- W2068697570 cites W2064530913 @default.
- W2068697570 cites W2072727514 @default.
- W2068697570 cites W2074613616 @default.
- W2068697570 cites W2097387406 @default.
- W2068697570 cites W2126682403 @default.
- W2068697570 cites W2136352499 @default.
- W2068697570 cites W2141502046 @default.
- W2068697570 cites W2150503531 @default.
- W2068697570 cites W2151409604 @default.
- W2068697570 cites W2160440373 @default.
- W2068697570 cites W2162826951 @default.
- W2068697570 cites W2167385903 @default.
- W2068697570 cites W2168206768 @default.
- W2068697570 cites W2224694077 @default.
- W2068697570 cites W4361867874 @default.
- W2068697570 doi "https://doi.org/10.1016/j.biomaterials.2013.03.053" @default.
- W2068697570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23578556" @default.
- W2068697570 hasPublicationYear "2013" @default.
- W2068697570 type Work @default.
- W2068697570 sameAs 2068697570 @default.
- W2068697570 citedByCount "147" @default.
- W2068697570 countsByYear W20686975702013 @default.
- W2068697570 countsByYear W20686975702014 @default.
- W2068697570 countsByYear W20686975702015 @default.
- W2068697570 countsByYear W20686975702016 @default.
- W2068697570 countsByYear W20686975702017 @default.
- W2068697570 countsByYear W20686975702018 @default.
- W2068697570 countsByYear W20686975702019 @default.
- W2068697570 countsByYear W20686975702020 @default.
- W2068697570 countsByYear W20686975702021 @default.
- W2068697570 countsByYear W20686975702022 @default.
- W2068697570 countsByYear W20686975702023 @default.
- W2068697570 crossrefType "journal-article" @default.
- W2068697570 hasAuthorship W2068697570A5001553975 @default.
- W2068697570 hasAuthorship W2068697570A5003048399 @default.
- W2068697570 hasAuthorship W2068697570A5011487190 @default.
- W2068697570 hasAuthorship W2068697570A5011866398 @default.
- W2068697570 hasAuthorship W2068697570A5043296871 @default.
- W2068697570 hasAuthorship W2068697570A5044038805 @default.
- W2068697570 hasAuthorship W2068697570A5049025559 @default.
- W2068697570 hasAuthorship W2068697570A5058333725 @default.
- W2068697570 hasConcept C127413603 @default.
- W2068697570 hasConcept C148318117 @default.
- W2068697570 hasConcept C156887251 @default.
- W2068697570 hasConcept C159985019 @default.
- W2068697570 hasConcept C171250308 @default.
- W2068697570 hasConcept C183586093 @default.
- W2068697570 hasConcept C192562407 @default.
- W2068697570 hasConcept C2778414984 @default.
- W2068697570 hasConcept C42360764 @default.
- W2068697570 hasConceptScore W2068697570C127413603 @default.
- W2068697570 hasConceptScore W2068697570C148318117 @default.
- W2068697570 hasConceptScore W2068697570C156887251 @default.
- W2068697570 hasConceptScore W2068697570C159985019 @default.
- W2068697570 hasConceptScore W2068697570C171250308 @default.
- W2068697570 hasConceptScore W2068697570C183586093 @default.
- W2068697570 hasConceptScore W2068697570C192562407 @default.
- W2068697570 hasConceptScore W2068697570C2778414984 @default.
- W2068697570 hasConceptScore W2068697570C42360764 @default.