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- W2068704885 abstract "Abstract 1. 1. A kinetic analysis of the incorporation of radiosulfate into pool and protein sulfur-containing amino acids by newly germinated, exponentially growing Neurospora crassa during a 3-h time period is reported. 2. 2. The initially 35S -labeled amino acids in the pool include cysteine, cystathionine, methionine, and homocysteine-cysteine disulfide and, in the cellular protein, cystine and methionine. A comparison of the specific activities of these compounds with each other suggests the following metabolic relationships. The data appear to rule out the sequence pool cysteine → cystathionine, and, also pool cysteine → pool and protein methionine. Pool cystathionine may contribute sulfur to the reactions leading to methionine formation. Pool methionine is probably directly converted to protein methionine. Cysteine and methionine biosynthetis do not appear to be directly linked. 3. 3. The isolation of [ 35 S]homocysteine-cysteine disulfide as an initially labeled metabolite is of interest because this is the first direct evidence for the presence of homocysteine in Neurospora." @default.
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- W2068704885 date "1966-04-01" @default.
- W2068704885 modified "2023-10-17" @default.
- W2068704885 title "Interrelationships of sulfur amino acids in the pool and cellular protein of Neurospora crassa" @default.
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- W2068704885 doi "https://doi.org/10.1016/0304-4165(66)90091-2" @default.
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