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- W2068706370 abstract "Abstract The cytotoxicity of peritoneal exudate cells from mice which had been injected with anaerobic coryneform organisms which have adjuvant activity was assessed by measuring the release of radioactive chromium from monolayers of whole mouse embryo cells. It was found that the peritoneal cells from adjuvant-stimulated mice were more cytotoxic than cells from normal mice. The increased cytotoxicity was present as early as 2 days after injection of the organisms, and was abolished by trypsin treatment of the peritoneal cells. The cytotoxic effect requires the presence of live peritoneal cells, and is more marked as the ratio of effector to target cells is increased. The plastic adherent cells of the peritoneal cell population are more effective in the cytotoxic reaction than are the non-adherent cells. The stimulated peritoneal cells can kill both syngeneic and allogeneic mouse embryo cells. Consideration is given to the possible mechanisms by which the increased cytotoxicity might be induced." @default.
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- W2068706370 date "1975-08-01" @default.
- W2068706370 modified "2023-09-25" @default.
- W2068706370 title "The in vitro killing of syngeneic cells by peritoneal cells from adjuvant-stimulated mice" @default.
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- W2068706370 doi "https://doi.org/10.1016/0008-8749(75)90066-0" @default.
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