FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068719985> ?p ?o ?g. }

• W2068719985 endingPage "30" @default.
• W2068719985 startingPage "19" @default.
• W2068719985 abstract "Pretherapy patients with chronic lymphocytic leukemia (CLL) from US Intergroup trial E2997 were analyzed with single nucleotide polymorphism microarrays to detect acquired chromosomal anomalies. The four CLL-typical anomalies (11q-, +12, 13q-, and 17p-) were found at expected frequencies. Acquired anomalies in other regions account for 70% of the total detected anomalies, and their number per participant has a significant effect on progression-free survival after adjusting for the effects of 17p- (and other covariates). These results were compared with those from a previous study of more than 50,000 participants from the GENEVA consortium of genome-wide association studies, which analyzed individuals with a variety of medical conditions and healthy controls. The percentage of individuals with acquired anomalies is vastly different between the two studies (GENEVA 0.8%; E2997 80%). The composition of the anomalies also differs, with GENEVA having a higher percentage of acquired uniparental disomies and a lower percentage of deletions. The four common CLL anomalies are among the most frequent in GENEVA participants, some of whom may have CLL-precursor conditions or early stages of CLL. However, the patients from E2997 (and other studies of symptomatic CLL) have recurrent acquired anomalies that were not found in GENEVA participants, thus identifying genomic changes that may be unique to symptomatic stages of CLL." @default.
• W2068719985 created "2016-06-24" @default.
• W2068719985 creator A5001124933 @default.
• W2068719985 creator A5001842538 @default.
• W2068719985 creator A5002515721 @default.
• W2068719985 creator A5004055647 @default.
• W2068719985 creator A5006201509 @default.
• W2068719985 creator A5011559739 @default.
• W2068719985 creator A5020668519 @default.
• W2068719985 creator A5033825180 @default.
• W2068719985 creator A5045392888 @default.
• W2068719985 creator A5047463043 @default.
• W2068719985 creator A5052582115 @default.
• W2068719985 creator A5062179230 @default.
• W2068719985 creator A5064012830 @default.
• W2068719985 creator A5065087784 @default.
• W2068719985 creator A5067154165 @default.
• W2068719985 creator A5079511754 @default.
• W2068719985 creator A5091905573 @default.
• W2068719985 date "2014-01-01" @default.
• W2068719985 modified "2023-09-26" @default.
• W2068719985 title "Acquired chromosomal anomalies in chronic lymphocytic leukemia patients compared with more than 50,000 quasi-normal participants" @default.
• W2068719985 cites W1574122583 @default.
• W2068719985 cites W1976814214 @default.
• W2068719985 cites W1985758276 @default.
• W2068719985 cites W1988340527 @default.
• W2068719985 cites W1993355130 @default.
• W2068719985 cites W2016047375 @default.
• W2068719985 cites W2021945943 @default.
• W2068719985 cites W2023830144 @default.
• W2068719985 cites W2024360770 @default.
• W2068719985 cites W2044433401 @default.
• W2068719985 cites W2049372901 @default.
• W2068719985 cites W2050886653 @default.
• W2068719985 cites W2055898543 @default.
• W2068719985 cites W2061445038 @default.
• W2068719985 cites W2063627118 @default.
• W2068719985 cites W2076367236 @default.
• W2068719985 cites W2085404468 @default.
• W2068719985 cites W2091168608 @default.
• W2068719985 cites W2093774016 @default.
• W2068719985 cites W2102187103 @default.
• W2068719985 cites W2109948920 @default.
• W2068719985 cites W2115577067 @default.
• W2068719985 cites W2116431837 @default.
• W2068719985 cites W2126442701 @default.
• W2068719985 cites W2127658533 @default.
• W2068719985 cites W2133920348 @default.
• W2068719985 cites W2140929811 @default.
• W2068719985 cites W2145777118 @default.
• W2068719985 cites W2146948473 @default.
• W2068719985 cites W2157596388 @default.
• W2068719985 cites W2158804744 @default.
• W2068719985 cites W2159578792 @default.
• W2068719985 cites W2318933236 @default.
• W2068719985 cites W2473561901 @default.
• W2068719985 cites W60865865 @default.
• W2068719985 doi "https://doi.org/10.1016/j.cancergen.2014.01.004" @default.
• W2068719985 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4074414" @default.
• W2068719985 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24613276" @default.
• W2068719985 hasPublicationYear "2014" @default.
• W2068719985 type Work @default.
• W2068719985 sameAs 2068719985 @default.
• W2068719985 citedByCount "5" @default.
• W2068719985 countsByYear W20687199852015 @default.
• W2068719985 countsByYear W20687199852016 @default.
• W2068719985 countsByYear W20687199852019 @default.
• W2068719985 crossrefType "journal-article" @default.
• W2068719985 hasAuthorship W2068719985A5001124933 @default.
• W2068719985 hasAuthorship W2068719985A5001842538 @default.
• W2068719985 hasAuthorship W2068719985A5002515721 @default.
• W2068719985 hasAuthorship W2068719985A5004055647 @default.
• W2068719985 hasAuthorship W2068719985A5006201509 @default.
• W2068719985 hasAuthorship W2068719985A5011559739 @default.
• W2068719985 hasAuthorship W2068719985A5020668519 @default.
• W2068719985 hasAuthorship W2068719985A5033825180 @default.
• W2068719985 hasAuthorship W2068719985A5045392888 @default.
• W2068719985 hasAuthorship W2068719985A5047463043 @default.
• W2068719985 hasAuthorship W2068719985A5052582115 @default.
• W2068719985 hasAuthorship W2068719985A5062179230 @default.
• W2068719985 hasAuthorship W2068719985A5064012830 @default.
• W2068719985 hasAuthorship W2068719985A5065087784 @default.
• W2068719985 hasAuthorship W2068719985A5067154165 @default.
• W2068719985 hasAuthorship W2068719985A5079511754 @default.
• W2068719985 hasAuthorship W2068719985A5091905573 @default.
• W2068719985 hasBestOaLocation W20687199852 @default.
• W2068719985 hasConcept C126322002 @default.
• W2068719985 hasConcept C2777938653 @default.
• W2068719985 hasConcept C2778461978 @default.
• W2068719985 hasConcept C71924100 @default.
• W2068719985 hasConceptScore W2068719985C126322002 @default.
• W2068719985 hasConceptScore W2068719985C2777938653 @default.
• W2068719985 hasConceptScore W2068719985C2778461978 @default.
• W2068719985 hasConceptScore W2068719985C71924100 @default.
• W2068719985 hasIssue "1-2" @default.
• W2068719985 hasLocation W20687199851 @default.
• W2068719985 hasLocation W20687199852 @default.
• W2068719985 hasLocation W20687199853 @default.

• next