Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068751730> ?p ?o ?g. }
- W2068751730 endingPage "569" @default.
- W2068751730 startingPage "562" @default.
- W2068751730 abstract "The spatial organization of the genome plays an important role in the regulation of nuclear functions and undergoes large scale changes during differentiation. These changes in the nuclear distribution of chromatin are, in a complex way, related to transcriptional status and epigenetic modifications. Recent studies emphasize the roles that gene promoters and alterations in replication timing play in the spatial reorganization of chromatin during cell differentiation. Changes in the association of chromatin regions with the nuclear lamina also emerge as a significant factor of transcriptional regulation. New results suggest that the spatial organization of chromatin in embryonic stem cells may be important for maintenance of the pluripotent state, whereas the nuclear architecture of differentiated cells facilitates formation of transcriptionally active zones with shared transcription and splicing machinery." @default.
- W2068751730 created "2016-06-24" @default.
- W2068751730 creator A5002041619 @default.
- W2068751730 creator A5031935199 @default.
- W2068751730 creator A5081645133 @default.
- W2068751730 date "2010-10-01" @default.
- W2068751730 modified "2023-09-26" @default.
- W2068751730 title "Differentiation and large scale spatial organization of the genome" @default.
- W2068751730 cites W1964129310 @default.
- W2068751730 cites W1968127700 @default.
- W2068751730 cites W1968554285 @default.
- W2068751730 cites W1970640134 @default.
- W2068751730 cites W1972043156 @default.
- W2068751730 cites W1975148822 @default.
- W2068751730 cites W1979245454 @default.
- W2068751730 cites W1979504761 @default.
- W2068751730 cites W1983921161 @default.
- W2068751730 cites W1984340155 @default.
- W2068751730 cites W1984479378 @default.
- W2068751730 cites W1986974894 @default.
- W2068751730 cites W1989855790 @default.
- W2068751730 cites W1991149014 @default.
- W2068751730 cites W1993570130 @default.
- W2068751730 cites W2000384908 @default.
- W2068751730 cites W2003777386 @default.
- W2068751730 cites W2017079604 @default.
- W2068751730 cites W2017840637 @default.
- W2068751730 cites W2019111498 @default.
- W2068751730 cites W2019160399 @default.
- W2068751730 cites W2019468853 @default.
- W2068751730 cites W2021919933 @default.
- W2068751730 cites W2022936555 @default.
- W2068751730 cites W2026180423 @default.
- W2068751730 cites W2038774969 @default.
- W2068751730 cites W2057341073 @default.
- W2068751730 cites W2059968749 @default.
- W2068751730 cites W2060355887 @default.
- W2068751730 cites W2063612621 @default.
- W2068751730 cites W2065189089 @default.
- W2068751730 cites W2075675349 @default.
- W2068751730 cites W2077254103 @default.
- W2068751730 cites W2082532751 @default.
- W2068751730 cites W2083886963 @default.
- W2068751730 cites W2085110456 @default.
- W2068751730 cites W2090037139 @default.
- W2068751730 cites W2091884937 @default.
- W2068751730 cites W2095736730 @default.
- W2068751730 cites W2099449240 @default.
- W2068751730 cites W2100805144 @default.
- W2068751730 cites W2101722176 @default.
- W2068751730 cites W2112124900 @default.
- W2068751730 cites W2114325184 @default.
- W2068751730 cites W2118416237 @default.
- W2068751730 cites W2124207075 @default.
- W2068751730 cites W2125734502 @default.
- W2068751730 cites W2127136309 @default.
- W2068751730 cites W2132090852 @default.
- W2068751730 cites W2132283906 @default.
- W2068751730 cites W2136285175 @default.
- W2068751730 cites W2138165389 @default.
- W2068751730 cites W2138784985 @default.
- W2068751730 cites W2143826692 @default.
- W2068751730 cites W2143922456 @default.
- W2068751730 cites W2144141448 @default.
- W2068751730 cites W2146470265 @default.
- W2068751730 cites W2147758798 @default.
- W2068751730 cites W2148486026 @default.
- W2068751730 cites W2149495099 @default.
- W2068751730 cites W2149974435 @default.
- W2068751730 cites W2150361747 @default.
- W2068751730 cites W2152152724 @default.
- W2068751730 cites W2152531901 @default.
- W2068751730 cites W2152853425 @default.
- W2068751730 cites W2153087859 @default.
- W2068751730 cites W2154855808 @default.
- W2068751730 cites W2155837532 @default.
- W2068751730 cites W2157251845 @default.
- W2068751730 cites W2162235906 @default.
- W2068751730 cites W2162362951 @default.
- W2068751730 cites W2162507985 @default.
- W2068751730 cites W4211071958 @default.
- W2068751730 doi "https://doi.org/10.1016/j.gde.2010.05.009" @default.
- W2068751730 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20561778" @default.
- W2068751730 hasPublicationYear "2010" @default.
- W2068751730 type Work @default.
- W2068751730 sameAs 2068751730 @default.
- W2068751730 citedByCount "63" @default.
- W2068751730 countsByYear W20687517302012 @default.
- W2068751730 countsByYear W20687517302013 @default.
- W2068751730 countsByYear W20687517302014 @default.
- W2068751730 countsByYear W20687517302015 @default.
- W2068751730 countsByYear W20687517302016 @default.
- W2068751730 countsByYear W20687517302017 @default.
- W2068751730 countsByYear W20687517302018 @default.
- W2068751730 countsByYear W20687517302019 @default.
- W2068751730 countsByYear W20687517302020 @default.
- W2068751730 countsByYear W20687517302021 @default.
- W2068751730 countsByYear W20687517302022 @default.