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- W2068754825 abstract "This study describes a proven case of German Measles (rubella) in a 15-year-old boy who developed an encephalomyelitic illness 7 days after the rash and which ended fatally 13 days later after a subacute course. Multiple foci of demyelination were seen in the spinal cord and brain which in appearance and distribution closely resembled multiple sclerosis plaques. The plaque in the lumbrosacral region, the oldest by clinical criteria, had undergone secondary haemorrhagic-spongio-necrotic degeneration which may have been related to terminal hypoxic changes. The case does not correspond to a disseminated encephalomyelitis of acute multiple sclerosis type or a more typical case of MS with exacerbations, and so may perhaps be more fittingly described as a post-exanthematous MS plaque syndrome in rubella. It is possible that damage to the CNS by birth trauma (ulegyria) may have resulted in immunopathological changes which combined with those of rubella to produce the unusual pathological picture." @default.
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- W2068754825 date "1972-03-01" @default.
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- W2068754825 title "“Multiple-sklerose”-plaques nach rubeolenerkrankung" @default.
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- W2068754825 doi "https://doi.org/10.1016/0022-510x(72)90074-3" @default.
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