FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068757005> ?p ?o ?g. }

• W2068757005 endingPage "117" @default.
• W2068757005 startingPage "102" @default.
• W2068757005 abstract "Current antiangiogenic therapy is limited by its cytostatic nature and systemic side effects. To address these limitations, we have unveiled the role of RhoJ, an endothelial-enriched Rho GTPase, during tumor progression. RhoJ blockade provides a double assault on tumor vessels by both inhibiting tumor angiogenesis and disrupting the preformed tumor vessels through the activation of the RhoA-ROCK (Rho kinase) signaling pathway in tumor endothelial cells, consequently resulting in a functional failure of tumor vasculatures. Moreover, enhanced anticancer effects were observed when RhoJ blockade was employed in concert with a cytotoxic chemotherapeutic agent, angiogenesis-inhibiting agent, or vascular-disrupting agent. These results identify RhoJ blockade as a selective and effective therapeutic strategy for targeting tumor vasculature with minimal side effects." @default.
• W2068757005 created "2016-06-24" @default.
• W2068757005 creator A5003106323 @default.
• W2068757005 creator A5034021674 @default.
• W2068757005 creator A5037879375 @default.
• W2068757005 creator A5041133038 @default.
• W2068757005 creator A5042188782 @default.
• W2068757005 creator A5049865258 @default.
• W2068757005 creator A5050403187 @default.
• W2068757005 creator A5055656957 @default.
• W2068757005 creator A5061682089 @default.
• W2068757005 creator A5063234359 @default.
• W2068757005 creator A5072702997 @default.
• W2068757005 creator A5079276210 @default.
• W2068757005 creator A5083665235 @default.
• W2068757005 creator A5089032664 @default.
• W2068757005 creator A5089863464 @default.
• W2068757005 creator A5091414721 @default.
• W2068757005 creator A5091509933 @default.
• W2068757005 date "2014-01-01" @default.
• W2068757005 modified "2023-10-16" @default.
• W2068757005 title "Vascular RhoJ Is an Effective and Selective Target for Tumor Angiogenesis and Vascular Disruption" @default.
• W2068757005 cites W1762724222 @default.
• W2068757005 cites W1966726954 @default.
• W2068757005 cites W1973096186 @default.
• W2068757005 cites W1975058097 @default.
• W2068757005 cites W1975669618 @default.
• W2068757005 cites W1977999028 @default.
• W2068757005 cites W1978148288 @default.
• W2068757005 cites W1983414413 @default.
• W2068757005 cites W1985804036 @default.
• W2068757005 cites W1992079665 @default.
• W2068757005 cites W1992112921 @default.
• W2068757005 cites W1992553297 @default.
• W2068757005 cites W2001216358 @default.
• W2068757005 cites W2012063336 @default.
• W2068757005 cites W2017322644 @default.
• W2068757005 cites W2024723528 @default.
• W2068757005 cites W2026184172 @default.
• W2068757005 cites W2034464991 @default.
• W2068757005 cites W2036564049 @default.
• W2068757005 cites W2037830708 @default.
• W2068757005 cites W2056326894 @default.
• W2068757005 cites W2056802932 @default.
• W2068757005 cites W2057663938 @default.
• W2068757005 cites W2072202404 @default.
• W2068757005 cites W2084740377 @default.
• W2068757005 cites W2089758247 @default.
• W2068757005 cites W2097177355 @default.
• W2068757005 cites W2101680696 @default.
• W2068757005 cites W2108455707 @default.
• W2068757005 cites W2108623236 @default.
• W2068757005 cites W2111628999 @default.
• W2068757005 cites W2112451265 @default.
• W2068757005 cites W2117241329 @default.
• W2068757005 cites W2117692326 @default.
• W2068757005 cites W2128560067 @default.
• W2068757005 cites W2139877124 @default.
• W2068757005 cites W2143852804 @default.
• W2068757005 cites W2154084248 @default.
• W2068757005 cites W2162352067 @default.
• W2068757005 cites W2165836181 @default.
• W2068757005 cites W2168202400 @default.
• W2068757005 doi "https://doi.org/10.1016/j.ccr.2013.12.010" @default.
• W2068757005 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24434213" @default.
• W2068757005 hasPublicationYear "2014" @default.
• W2068757005 type Work @default.
• W2068757005 sameAs 2068757005 @default.
• W2068757005 citedByCount "107" @default.
• W2068757005 countsByYear W20687570052014 @default.
• W2068757005 countsByYear W20687570052015 @default.
• W2068757005 countsByYear W20687570052016 @default.
• W2068757005 countsByYear W20687570052017 @default.
• W2068757005 countsByYear W20687570052018 @default.
• W2068757005 countsByYear W20687570052019 @default.
• W2068757005 countsByYear W20687570052020 @default.
• W2068757005 countsByYear W20687570052021 @default.
• W2068757005 countsByYear W20687570052022 @default.
• W2068757005 countsByYear W20687570052023 @default.
• W2068757005 crossrefType "journal-article" @default.
• W2068757005 hasAuthorship W2068757005A5003106323 @default.
• W2068757005 hasAuthorship W2068757005A5034021674 @default.
• W2068757005 hasAuthorship W2068757005A5037879375 @default.
• W2068757005 hasAuthorship W2068757005A5041133038 @default.
• W2068757005 hasAuthorship W2068757005A5042188782 @default.
• W2068757005 hasAuthorship W2068757005A5049865258 @default.
• W2068757005 hasAuthorship W2068757005A5050403187 @default.
• W2068757005 hasAuthorship W2068757005A5055656957 @default.
• W2068757005 hasAuthorship W2068757005A5061682089 @default.
• W2068757005 hasAuthorship W2068757005A5063234359 @default.
• W2068757005 hasAuthorship W2068757005A5072702997 @default.
• W2068757005 hasAuthorship W2068757005A5079276210 @default.
• W2068757005 hasAuthorship W2068757005A5083665235 @default.
• W2068757005 hasAuthorship W2068757005A5089032664 @default.
• W2068757005 hasAuthorship W2068757005A5089863464 @default.
• W2068757005 hasAuthorship W2068757005A5091414721 @default.
• W2068757005 hasAuthorship W2068757005A5091509933 @default.
• W2068757005 hasBestOaLocation W20687570051 @default.

• next