FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068792556> ?p ?o ?g. }

• W2068792556 abstract "A high-angle X-ray fibre diffraction study of a tubercidin analogue of the poly[d(A-T)].poly[d(A-T)] DNA double helix has been carried out using station 7.2 at the Daresbury Laboratory synchrotron radiation source. The polymer has been studied for a wide range of salt strengths and hydration conditions and exhibits conformational polymorphism that is quite distinct from that observed for the unmodified polymer. The replacement of deoxyadenosine by deoxytubercidin in the polynucleotide causes only slight alterations to the structure of A-DNA, but significantly alters the structure of the B conformation. Additionally, the modified polymer does not, in any conditions yet identified, adopt the D conformation. In conditions which would normally favour the D conformation of poly[d(A-T)].poly[d(A-T)], the modified polymer adopts an unusual conformation which is designated here as the K conformation. These observations are important for an understanding of major groove interactions involved in the stabilisation of particular DNA conformations and also more generally for an insight into the pharmacological activity of tubercidin which following its incorporation into nucleic acids may cause stereochemical distortions of the DNA double helix." @default.
• W2068792556 created "2016-06-24" @default.
• W2068792556 creator A5007332304 @default.
• W2068792556 creator A5010498781 @default.
• W2068792556 creator A5035734508 @default.
• W2068792556 creator A5057359276 @default.
• W2068792556 creator A5059386061 @default.
• W2068792556 creator A5084188351 @default.
• W2068792556 date "1998-02-01" @default.
• W2068792556 modified "2023-09-27" @default.
• W2068792556 title "Structural polymorphism in a tubercidin analogue of the DNA double helix" @default.
• W2068792556 cites W1487858645 @default.
• W2068792556 cites W1500960442 @default.
• W2068792556 cites W1547001327 @default.
• W2068792556 cites W1582727954 @default.
• W2068792556 cites W1755459697 @default.
• W2068792556 cites W1968251916 @default.
• W2068792556 cites W1974767569 @default.
• W2068792556 cites W1988653143 @default.
• W2068792556 cites W1990071033 @default.
• W2068792556 cites W1990556570 @default.
• W2068792556 cites W1997650976 @default.
• W2068792556 cites W2002863536 @default.
• W2068792556 cites W2011703379 @default.
• W2068792556 cites W2011844193 @default.
• W2068792556 cites W2013705185 @default.
• W2068792556 cites W2027677803 @default.
• W2068792556 cites W2034747755 @default.
• W2068792556 cites W2034933375 @default.
• W2068792556 cites W2041081539 @default.
• W2068792556 cites W2047898790 @default.
• W2068792556 cites W2048562981 @default.
• W2068792556 cites W2052865902 @default.
• W2068792556 cites W2053954575 @default.
• W2068792556 cites W2060993396 @default.
• W2068792556 cites W2071198460 @default.
• W2068792556 cites W2080631871 @default.
• W2068792556 cites W2089333046 @default.
• W2068792556 cites W2089811070 @default.
• W2068792556 cites W2091643064 @default.
• W2068792556 cites W2093745752 @default.
• W2068792556 cites W2123472832 @default.
• W2068792556 cites W2171074980 @default.
• W2068792556 cites W2307269906 @default.
• W2068792556 doi "https://doi.org/10.1016/s0301-4622(97)00132-4" @default.
• W2068792556 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9540207" @default.
• W2068792556 hasPublicationYear "1998" @default.
• W2068792556 type Work @default.
• W2068792556 sameAs 2068792556 @default.
• W2068792556 citedByCount "8" @default.
• W2068792556 countsByYear W20687925562013 @default.
• W2068792556 crossrefType "journal-article" @default.
• W2068792556 hasAuthorship W2068792556A5007332304 @default.
• W2068792556 hasAuthorship W2068792556A5010498781 @default.
• W2068792556 hasAuthorship W2068792556A5035734508 @default.
• W2068792556 hasAuthorship W2068792556A5057359276 @default.
• W2068792556 hasAuthorship W2068792556A5059386061 @default.
• W2068792556 hasAuthorship W2068792556A5084188351 @default.
• W2068792556 hasConcept C104317684 @default.
• W2068792556 hasConcept C111921641 @default.
• W2068792556 hasConcept C120665830 @default.
• W2068792556 hasConcept C121332964 @default.
• W2068792556 hasConcept C12554922 @default.
• W2068792556 hasConcept C135763542 @default.
• W2068792556 hasConcept C149737253 @default.
• W2068792556 hasConcept C178790620 @default.
• W2068792556 hasConcept C185544564 @default.
• W2068792556 hasConcept C185592680 @default.
• W2068792556 hasConcept C18903297 @default.
• W2068792556 hasConcept C207114421 @default.
• W2068792556 hasConcept C21368211 @default.
• W2068792556 hasConcept C24107716 @default.
• W2068792556 hasConcept C2778530040 @default.
• W2068792556 hasConcept C2779965526 @default.
• W2068792556 hasConcept C50515024 @default.
• W2068792556 hasConcept C521977710 @default.
• W2068792556 hasConcept C552990157 @default.
• W2068792556 hasConcept C55493867 @default.
• W2068792556 hasConcept C65636608 @default.
• W2068792556 hasConcept C71240020 @default.
• W2068792556 hasConcept C8010536 @default.
• W2068792556 hasConcept C86803240 @default.
• W2068792556 hasConceptScore W2068792556C104317684 @default.
• W2068792556 hasConceptScore W2068792556C111921641 @default.
• W2068792556 hasConceptScore W2068792556C120665830 @default.
• W2068792556 hasConceptScore W2068792556C121332964 @default.
• W2068792556 hasConceptScore W2068792556C12554922 @default.
• W2068792556 hasConceptScore W2068792556C135763542 @default.
• W2068792556 hasConceptScore W2068792556C149737253 @default.
• W2068792556 hasConceptScore W2068792556C178790620 @default.
• W2068792556 hasConceptScore W2068792556C185544564 @default.
• W2068792556 hasConceptScore W2068792556C185592680 @default.
• W2068792556 hasConceptScore W2068792556C18903297 @default.
• W2068792556 hasConceptScore W2068792556C207114421 @default.
• W2068792556 hasConceptScore W2068792556C21368211 @default.
• W2068792556 hasConceptScore W2068792556C24107716 @default.
• W2068792556 hasConceptScore W2068792556C2778530040 @default.
• W2068792556 hasConceptScore W2068792556C2779965526 @default.
• W2068792556 hasConceptScore W2068792556C50515024 @default.
• W2068792556 hasConceptScore W2068792556C521977710 @default.

• next