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• W2068796466 abstract "Approximately one-third of drugs prescribed in the United States may be unnecessary. 1 Weiner B.J. Alexander J.A. Shortell S.M. et al. Quality improvement implementation and hospital performance on quality indicators. Health Serv Res. 2006; 41: 307-334 Crossref PubMed Scopus (112) Google Scholar Older adults use higher numbers of medications compared with younger age groups, primarily because of increased numbers of comorbid conditions and greater numbers of physicians involved in their care, putting them at higher risk of polypharmacy. The use of multiple medications increases the risk for adverse drug events and adverse health outcomes. 2 Reason B. Terner M. Moses McKeag A. et al. The impact of polypharmacy on the health of Canadian seniors. Family Pract. 2012; ([Epub ahead of print]) PubMed Google Scholar , 3 Richardson K. Ananou A. Lafortune L. et al. Variation over time in the association between polypharmacy and mortality in the older population. Drugs Aging. 2011; 28: 547-560 Crossref PubMed Scopus (66) Google Scholar Medication management is of utmost significance in older adults because of changes in body composition, physical function, social environment, and limiting finances with increasing age. Adding or stopping a medication in an older person should focus on improving function or quality of life, a core principle in the management of chronic illnesses in the elderly (Box 1). Polypharmacy is defined as the use of multiple medications or duplicative medications that cause increased risk for drug-drug and drug-disease interactions. Polymedicine or polytherapy describes the use of multiple medications prescribed appropriately for treating multiple comorbid conditions. The prescribing cascade refers to the use of a medication that results in an adverse drug event that is mistaken for a new diagnosis and treated with another medication, thus, increasing the risk for further adverse drug events. Polypharmacy is defined as the use of multiple medications or duplicative medications that cause increased risk for drug-drug and drug-disease interactions. Polymedicine or polytherapy describes the use of multiple medications prescribed appropriately for treating multiple comorbid conditions. The prescribing cascade refers to the use of a medication that results in an adverse drug event that is mistaken for a new diagnosis and treated with another medication, thus, increasing the risk for further adverse drug events." @default.
• W2068796466 created "2016-06-24" @default.
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• W2068796466 date "2012-05-01" @default.
• W2068796466 modified "2023-10-03" @default.
• W2068796466 title "Tools to Reduce Polypharmacy" @default.
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• W2068796466 doi "https://doi.org/10.1016/j.cger.2012.01.011" @default.
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