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- W2068804477 abstract "Neocortical and hippocampal electroencephalographic (EEC) activity were recorded from rats during: (a) spontaneous activities, (b) paralysis produced by curare or gallamine neuromuscular blockade, and (c) urethane anesthesia. All of the patterns of EEG recorded from normal rats were obtained from paralyzed rats including: (a) atropine resistant neocortical desynchronization and fast (6–12 Hz) hippocampal rhythmical slow activity (RSA) normally associated with overt Type I or voluntary movement, (b) atropine sensitive and urethane resistant slow (4–6 Hz) RSA which can be recorded from immobile animals during conditioning procedures, or during brain or sensory stimulation, and (c) large amplitude irregular neocortical and hippocampal EEG which can be recorded from immobile or sleeping animals. Depth profiles of RSA were taken from the hippocampal formation of urethanized and curarized rats during posterior hypothalamic stimulation. The results confirmed findings of two RSA amplitude maxima with an approximate 180° phase difference, one location in stratum oriens of area CA-1, the other in stratum moleculare of the dentate gyrus, and suggest there are two generators of RSA. Atropine sensitive and atropine resistant types of RSA were found in each generator. The results suggest that RSA may be supported by both cholinergic and noncholinergic input to each generator and that neither RSA type could be only the result of proprioceptive feedback from joints or muscles." @default.
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- W2068804477 date "1976-11-01" @default.
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- W2068804477 title "Neuromuscular blockade: The effects on two hippocampal RSA (theta) systems and neocortical desynchronization" @default.
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- W2068804477 doi "https://doi.org/10.1016/0361-9230(76)90084-8" @default.
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