FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068806426> ?p ?o ?g. }

• W2068806426 endingPage "1244" @default.
• W2068806426 startingPage "1236" @default.
• W2068806426 abstract "A subchronic toxicity study of water pepper extract (WPE) from Polygonum hydropiper L. was conducted in groups of 10 male and 10 female F344 rats fed powdered diets containing 0, 62.5, 250, 1000 or 4000 ppm concentrations for 13 weeks. Suppression of body weight gain due to decreased food consumption was observed in both sexes at 4000 ppm, and at autopsy, increase of relative weights was observed for the brain, liver, spleen, kidneys, and testes in these animals, suggestive of the reflection of the reduced body weights. At this dose, slight increases of blood urea nitrogen in both sexes and serum alanine aminotransferase, Na and Cl in females, were observed, suggestive of weak hepatic and renal toxicity, at least in females. The same females also exhibited slight decrease of red blood cells and haematocrit, slight increase of mean corpuscular volume and mean corpuscular haemoglobin, and minimal increase of splenic haemosiderin deposition, providing evidence of slight haemolytic anemia. On the other hand, enhanced accumulation of mast cells was observed in the mesenteric lymph nodes at 4000 ppm in males and 1000 and 4000 ppm in females. Considering the anti-anaphylactic properties of polygodial, a major constituent of WPE, the mast cell accumulation was concluded to be an adaptive change in response to the subchronic oral administration of WPE. Based on the present toxicity data, 1000 ppm was determined to be the no-observed-adverse-effect level, translating into 57.4 and 62.9 mg/kg/day for male and female rats, respectively." @default.
• W2068806426 created "2016-06-24" @default.
• W2068806426 creator A5004728236 @default.
• W2068806426 creator A5041911355 @default.
• W2068806426 creator A5054905731 @default.
• W2068806426 creator A5062202170 @default.
• W2068806426 creator A5083010092 @default.
• W2068806426 creator A5086510111 @default.
• W2068806426 date "2006-08-01" @default.
• W2068806426 modified "2023-09-25" @default.
• W2068806426 title "Subchronic toxicity study of water pepper extract in F344 rats" @default.
• W2068806426 cites W1972656091 @default.
• W2068806426 cites W1986036278 @default.
• W2068806426 cites W1986802509 @default.
• W2068806426 cites W1987418164 @default.
• W2068806426 cites W1988239155 @default.
• W2068806426 cites W1997939391 @default.
• W2068806426 cites W2002554362 @default.
• W2068806426 cites W2029384174 @default.
• W2068806426 cites W2050306951 @default.
• W2068806426 cites W2057817995 @default.
• W2068806426 cites W2065661282 @default.
• W2068806426 cites W2066774498 @default.
• W2068806426 cites W2077612148 @default.
• W2068806426 cites W2084010303 @default.
• W2068806426 cites W2084702239 @default.
• W2068806426 cites W2092144921 @default.
• W2068806426 cites W2126853108 @default.
• W2068806426 cites W2135157747 @default.
• W2068806426 cites W2246553193 @default.
• W2068806426 cites W2326755751 @default.
• W2068806426 cites W2766368224 @default.
• W2068806426 doi "https://doi.org/10.1016/j.fct.2006.01.020" @default.
• W2068806426 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16542768" @default.
• W2068806426 hasPublicationYear "2006" @default.
• W2068806426 type Work @default.
• W2068806426 sameAs 2068806426 @default.
• W2068806426 citedByCount "15" @default.
• W2068806426 countsByYear W20688064262012 @default.
• W2068806426 countsByYear W20688064262013 @default.
• W2068806426 countsByYear W20688064262014 @default.
• W2068806426 countsByYear W20688064262016 @default.
• W2068806426 countsByYear W20688064262017 @default.
• W2068806426 countsByYear W20688064262020 @default.
• W2068806426 countsByYear W20688064262022 @default.
• W2068806426 crossrefType "journal-article" @default.
• W2068806426 hasAuthorship W2068806426A5004728236 @default.
• W2068806426 hasAuthorship W2068806426A5041911355 @default.
• W2068806426 hasAuthorship W2068806426A5054905731 @default.
• W2068806426 hasAuthorship W2068806426A5062202170 @default.
• W2068806426 hasAuthorship W2068806426A5083010092 @default.
• W2068806426 hasAuthorship W2068806426A5086510111 @default.
• W2068806426 hasConcept C126322002 @default.
• W2068806426 hasConcept C134018914 @default.
• W2068806426 hasConcept C142724271 @default.
• W2068806426 hasConcept C185592680 @default.
• W2068806426 hasConcept C2776242653 @default.
• W2068806426 hasConcept C2777056448 @default.
• W2068806426 hasConcept C2777092883 @default.
• W2068806426 hasConcept C2778176769 @default.
• W2068806426 hasConcept C2778917026 @default.
• W2068806426 hasConcept C2779720271 @default.
• W2068806426 hasConcept C2779797417 @default.
• W2068806426 hasConcept C2780306776 @default.
• W2068806426 hasConcept C2780931953 @default.
• W2068806426 hasConcept C2781058662 @default.
• W2068806426 hasConcept C29730261 @default.
• W2068806426 hasConcept C31903555 @default.
• W2068806426 hasConcept C71924100 @default.
• W2068806426 hasConceptScore W2068806426C126322002 @default.
• W2068806426 hasConceptScore W2068806426C134018914 @default.
• W2068806426 hasConceptScore W2068806426C142724271 @default.
• W2068806426 hasConceptScore W2068806426C185592680 @default.
• W2068806426 hasConceptScore W2068806426C2776242653 @default.
• W2068806426 hasConceptScore W2068806426C2777056448 @default.
• W2068806426 hasConceptScore W2068806426C2777092883 @default.
• W2068806426 hasConceptScore W2068806426C2778176769 @default.
• W2068806426 hasConceptScore W2068806426C2778917026 @default.
• W2068806426 hasConceptScore W2068806426C2779720271 @default.
• W2068806426 hasConceptScore W2068806426C2779797417 @default.
• W2068806426 hasConceptScore W2068806426C2780306776 @default.
• W2068806426 hasConceptScore W2068806426C2780931953 @default.
• W2068806426 hasConceptScore W2068806426C2781058662 @default.
• W2068806426 hasConceptScore W2068806426C29730261 @default.
• W2068806426 hasConceptScore W2068806426C31903555 @default.
• W2068806426 hasConceptScore W2068806426C71924100 @default.
• W2068806426 hasIssue "8" @default.
• W2068806426 hasLocation W20688064261 @default.
• W2068806426 hasLocation W20688064262 @default.
• W2068806426 hasOpenAccess W2068806426 @default.
• W2068806426 hasPrimaryLocation W20688064261 @default.
• W2068806426 hasRelatedWork W1970861121 @default.
• W2068806426 hasRelatedWork W1984302352 @default.
• W2068806426 hasRelatedWork W1986049049 @default.
• W2068806426 hasRelatedWork W2018156761 @default.
• W2068806426 hasRelatedWork W2023206717 @default.
• W2068806426 hasRelatedWork W2049047086 @default.
• W2068806426 hasRelatedWork W2057552018 @default.

• next