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- W2068807504 abstract "The influence of vasodilators in the natural history ofmitral regurgitation is controversial. If, on the one hand,they may really interfere, on the other, they may mask leftventricular myocardial dysfunction.Three phases comprise the natural history of mitral re-gurgitation. In the first, increased atrial compliance and ec-centric ventricular hypertrophy are observed in associationwith diastolic normotension. In the second phase, a transi-tion phase, a slow increase in diastolic and left chamber pres-sures is observed. In the third phase, handicapping symp-toms occur due to failure in compensating mechanisms andelevation in the systolic and pulmonary pressures.It is estimated that up to 82% of the patients with mitralregurgitation due to prolapse progress to surgical indicationin a 10-year period, which is equivalent to a 20% rate of sur-gical indication per year" @default.
- W2068807504 created "2016-06-24" @default.
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- W2068807504 date "2002-09-01" @default.
- W2068807504 modified "2023-09-25" @default.
- W2068807504 title "Do Vasodilators Interfere with Left Ventricular Remodeling in Chronic Mitral Regurgitation?" @default.
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- W2068807504 doi "https://doi.org/10.1590/s0066-782x2002001200001" @default.
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