Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068807853> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2068807853 endingPage "405" @default.
- W2068807853 startingPage "400" @default.
- W2068807853 abstract "A bstract : Treatment with 6‐hydroxydopamine significantly reduced the viability of cultured rat primary astrocytes, rat astrocytoma cell line C6, and human astrocytoma cell line U251. 6‐Hydroxydopamine‐treated astrocytes exhibited altered nuclear morphology, DNA fragmentation, and reduced intracellular esterase activity, which indicated apoptotic cell death. Astrocytes were protected by neutralization of 6‐hydroxydopamine autooxidation products H 2 O 2 , O 2 •− , and • OH, but not by cell‐derived or chemically generated anti‐apoptotic free radical nitric oxide. Finally, 6‐hydroxydopamine activated extracellular signal‐regulated kinase in astrocytes and selective inhibitor of extracellular signal‐regulated kinase activation partially prevented astrocyte death. Taken together, these data indicate that 6‐hydroxydopamine‐triggered oxidative stress induces extracellular signal‐regulated kinase‐dependent apoptotic death of astrocytes." @default.
- W2068807853 created "2016-06-24" @default.
- W2068807853 creator A5017676012 @default.
- W2068807853 creator A5045015673 @default.
- W2068807853 creator A5056923394 @default.
- W2068807853 creator A5057043868 @default.
- W2068807853 creator A5070648885 @default.
- W2068807853 date "2005-06-01" @default.
- W2068807853 modified "2023-10-14" @default.
- W2068807853 title "The Mechanisms of 6-Hydroxydopamine-Induced Astrocyte Death" @default.
- W2068807853 cites W1594281994 @default.
- W2068807853 cites W1668344921 @default.
- W2068807853 cites W1907726557 @default.
- W2068807853 cites W1988968910 @default.
- W2068807853 cites W2033317847 @default.
- W2068807853 cites W2049157042 @default.
- W2068807853 cites W2054701937 @default.
- W2068807853 cites W2059994807 @default.
- W2068807853 cites W2079231229 @default.
- W2068807853 cites W2089924484 @default.
- W2068807853 cites W2136519986 @default.
- W2068807853 cites W2142800498 @default.
- W2068807853 cites W55958259 @default.
- W2068807853 doi "https://doi.org/10.1196/annals.1342.049" @default.
- W2068807853 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16154962" @default.
- W2068807853 hasPublicationYear "2005" @default.
- W2068807853 type Work @default.
- W2068807853 sameAs 2068807853 @default.
- W2068807853 citedByCount "7" @default.
- W2068807853 countsByYear W20688078532012 @default.
- W2068807853 countsByYear W20688078532015 @default.
- W2068807853 countsByYear W20688078532017 @default.
- W2068807853 countsByYear W20688078532018 @default.
- W2068807853 countsByYear W20688078532021 @default.
- W2068807853 crossrefType "journal-article" @default.
- W2068807853 hasAuthorship W2068807853A5017676012 @default.
- W2068807853 hasAuthorship W2068807853A5045015673 @default.
- W2068807853 hasAuthorship W2068807853A5056923394 @default.
- W2068807853 hasAuthorship W2068807853A5057043868 @default.
- W2068807853 hasAuthorship W2068807853A5070648885 @default.
- W2068807853 hasConcept C137183658 @default.
- W2068807853 hasConcept C153911025 @default.
- W2068807853 hasConcept C169760540 @default.
- W2068807853 hasConcept C184235292 @default.
- W2068807853 hasConcept C185592680 @default.
- W2068807853 hasConcept C18903297 @default.
- W2068807853 hasConcept C190283241 @default.
- W2068807853 hasConcept C191015642 @default.
- W2068807853 hasConcept C2777542381 @default.
- W2068807853 hasConcept C28406088 @default.
- W2068807853 hasConcept C2911016594 @default.
- W2068807853 hasConcept C31573885 @default.
- W2068807853 hasConcept C43759708 @default.
- W2068807853 hasConcept C513476851 @default.
- W2068807853 hasConcept C529278444 @default.
- W2068807853 hasConcept C55493867 @default.
- W2068807853 hasConcept C79879829 @default.
- W2068807853 hasConcept C86803240 @default.
- W2068807853 hasConcept C95444343 @default.
- W2068807853 hasConceptScore W2068807853C137183658 @default.
- W2068807853 hasConceptScore W2068807853C153911025 @default.
- W2068807853 hasConceptScore W2068807853C169760540 @default.
- W2068807853 hasConceptScore W2068807853C184235292 @default.
- W2068807853 hasConceptScore W2068807853C185592680 @default.
- W2068807853 hasConceptScore W2068807853C18903297 @default.
- W2068807853 hasConceptScore W2068807853C190283241 @default.
- W2068807853 hasConceptScore W2068807853C191015642 @default.
- W2068807853 hasConceptScore W2068807853C2777542381 @default.
- W2068807853 hasConceptScore W2068807853C28406088 @default.
- W2068807853 hasConceptScore W2068807853C2911016594 @default.
- W2068807853 hasConceptScore W2068807853C31573885 @default.
- W2068807853 hasConceptScore W2068807853C43759708 @default.
- W2068807853 hasConceptScore W2068807853C513476851 @default.
- W2068807853 hasConceptScore W2068807853C529278444 @default.
- W2068807853 hasConceptScore W2068807853C55493867 @default.
- W2068807853 hasConceptScore W2068807853C79879829 @default.
- W2068807853 hasConceptScore W2068807853C86803240 @default.
- W2068807853 hasConceptScore W2068807853C95444343 @default.
- W2068807853 hasIssue "1" @default.
- W2068807853 hasLocation W20688078531 @default.
- W2068807853 hasLocation W20688078532 @default.
- W2068807853 hasOpenAccess W2068807853 @default.
- W2068807853 hasPrimaryLocation W20688078531 @default.
- W2068807853 hasRelatedWork W1432933144 @default.
- W2068807853 hasRelatedWork W1972094490 @default.
- W2068807853 hasRelatedWork W1996044582 @default.
- W2068807853 hasRelatedWork W2033803187 @default.
- W2068807853 hasRelatedWork W2117519097 @default.
- W2068807853 hasRelatedWork W2161791039 @default.
- W2068807853 hasRelatedWork W2352517883 @default.
- W2068807853 hasRelatedWork W2382167159 @default.
- W2068807853 hasRelatedWork W33711824 @default.
- W2068807853 hasRelatedWork W4241014707 @default.
- W2068807853 hasVolume "1048" @default.
- W2068807853 isParatext "false" @default.
- W2068807853 isRetracted "false" @default.
- W2068807853 magId "2068807853" @default.
- W2068807853 workType "article" @default.