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- W2068828209 abstract "Iron deficiency anemia is one of the most common nutritional disorders in childhood and women of the reproductive age. Several clinical and experimental studies suggest that many immune functions which include delayed type hypersensitivity, mitogenic response, cytotoxicity of T cells and natural killer cells, bactericidal activity of leukocytes, etc., are impaired. However, as to how this impairment is related to susceptibility to infections is still uncertain since iron is required by many microorganisms for cell division. Several clinical studies have suggested that iron deficiency predisposes to infections and iron therapy restores resistance. Other studies have shown the opposite. This review carefully analyzes many of the studies which have shown an association or lack of association between iron status and/or iron therapy and incidence of infections. Reasons for the controversies are also discussed." @default.
- W2068828209 created "2016-06-24" @default.
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- W2068828209 date "1987-09-01" @default.
- W2068828209 modified "2023-10-16" @default.
- W2068828209 title "Iron deficiency, cell-mediated immunity and resistance against infections: Present knowledge and controversies" @default.
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- W2068828209 doi "https://doi.org/10.1016/s0271-5317(87)80169-0" @default.
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