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- W2068838757 abstract "Controlled positive-pressure ventilation with added positive end-expiratory pressure (PEEP) is a major method of therapy for the severe hypoxemia associated with pulmonary edema, especially that associated with the persistent pulmonary edema caused by lung-capillary injury and increased capillary permeability.1 Although PEEP raises arterial oxygen tension and content in this setting, it may also lower cardiac output.2 Thus, PEEP has opposing influences on oxygen delivery to the tissues, since oxygen transport depends on the product of arterial oxygen content and cardiac output. A precise understanding of the mechanisms by which PEEP reduces cardiac output might allow more appropriate therapy. This issue . . ." @default.
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- W2068838757 date "1981-02-12" @default.
- W2068838757 modified "2023-09-24" @default.
- W2068838757 title "A Perspective on PEEP" @default.
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- W2068838757 doi "https://doi.org/10.1056/nejm198102123040710" @default.
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