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- W2068852589 abstract "A simple synthesis of tricyclic analogues of the quinolone antibiotics bearing a diverse range of substituents on the aromatic ring is described. The key steps involve unprecedented Reformatsky reaction between diethyl bromomalonate and N-arylpyrrolidine-2-thiones 8, followed by cyclisation of the resulting enaminone intermediates 9 in polyphosphoric acid." @default.
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- W2068852589 date "1996-12-01" @default.
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- W2068852589 title "A versatile synthesis of tricyclic analogues of quinolone antibacterial agents: Use of a novel reformatsky reaction" @default.
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- W2068852589 doi "https://doi.org/10.1016/s0040-4039(97)82976-0" @default.
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