Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068877544> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2068877544 endingPage "611" @default.
- W2068877544 startingPage "603" @default.
- W2068877544 abstract "The feedback effects of dihydrotestosterone (DHT) on gonadotropin secretion in rams were investigated using DHT-implanted castrate rams (wethers) infused with intermittent pulsatile luteinizing hormone-releasing hormone (LHRH) for 14 days. Castration, as anticipated, reduced both serum testosterone and DHT but elevated serum LH and follicle-stimulating hormone (FSH). Dihydrotestosterone implants raised serum DHT in wethers to intact ram levels and blocked the LH and FSH response to castration. The secretory profile of these individuals failed to show an endogenous LH pulse during any of the scheduled blood sampling periods, but a small LH pulse was observed following a 5-ng/kg LHRH challenge injection. Dihydrotestosterone-implanted wethers given repeated LHRH injections beginning at the time of castration increased serum FSH and yielded LH pulses that were temporally coupled to exogenous LHRH administration. While the frequency of these secretory episodes was comparable to that observed for castrates, amplitudes of the induced LH pulses were blunted relative to those observed for similarly infused, testosterone-implanted castrates. Dihydrotestosterone was also shown to inhibit LH and FSH secretion and serum testosterone concentrations in intact rams. In summary, it appears that DHT may normally participate in feedback regulation of LH and FSH secretion in rams. These data suggest androgen feedback is regulated by deceleration of the hypothalamic LHRH pulse generator and direct actions at the level of the adenohypophysis." @default.
- W2068877544 created "2016-06-24" @default.
- W2068877544 creator A5072318644 @default.
- W2068877544 date "1985-10-01" @default.
- W2068877544 modified "2023-10-14" @default.
- W2068877544 title "Effects of Intermittent Pulsatile Infusion of Luteinizing Hormonereleasing Hormone on Dihydrotestosterone-suppressed Gonadotropin Secretion in Castrate Rams" @default.
- W2068877544 doi "https://doi.org/10.1095/biolreprod33.3.603" @default.
- W2068877544 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3931708" @default.
- W2068877544 hasPublicationYear "1985" @default.
- W2068877544 type Work @default.
- W2068877544 sameAs 2068877544 @default.
- W2068877544 citedByCount "12" @default.
- W2068877544 crossrefType "journal-article" @default.
- W2068877544 hasAuthorship W2068877544A5072318644 @default.
- W2068877544 hasBestOaLocation W20688775441 @default.
- W2068877544 hasConcept C126322002 @default.
- W2068877544 hasConcept C134018914 @default.
- W2068877544 hasConcept C2777911890 @default.
- W2068877544 hasConcept C2778575703 @default.
- W2068877544 hasConcept C2778782382 @default.
- W2068877544 hasConcept C2778894405 @default.
- W2068877544 hasConcept C2779256933 @default.
- W2068877544 hasConcept C2779279991 @default.
- W2068877544 hasConcept C2779881493 @default.
- W2068877544 hasConcept C49039625 @default.
- W2068877544 hasConcept C71315377 @default.
- W2068877544 hasConcept C71924100 @default.
- W2068877544 hasConcept C79191276 @default.
- W2068877544 hasConcept C86803240 @default.
- W2068877544 hasConceptScore W2068877544C126322002 @default.
- W2068877544 hasConceptScore W2068877544C134018914 @default.
- W2068877544 hasConceptScore W2068877544C2777911890 @default.
- W2068877544 hasConceptScore W2068877544C2778575703 @default.
- W2068877544 hasConceptScore W2068877544C2778782382 @default.
- W2068877544 hasConceptScore W2068877544C2778894405 @default.
- W2068877544 hasConceptScore W2068877544C2779256933 @default.
- W2068877544 hasConceptScore W2068877544C2779279991 @default.
- W2068877544 hasConceptScore W2068877544C2779881493 @default.
- W2068877544 hasConceptScore W2068877544C49039625 @default.
- W2068877544 hasConceptScore W2068877544C71315377 @default.
- W2068877544 hasConceptScore W2068877544C71924100 @default.
- W2068877544 hasConceptScore W2068877544C79191276 @default.
- W2068877544 hasConceptScore W2068877544C86803240 @default.
- W2068877544 hasIssue "3" @default.
- W2068877544 hasLocation W20688775441 @default.
- W2068877544 hasLocation W20688775442 @default.
- W2068877544 hasOpenAccess W2068877544 @default.
- W2068877544 hasPrimaryLocation W20688775441 @default.
- W2068877544 hasRelatedWork W100906039 @default.
- W2068877544 hasRelatedWork W1521559908 @default.
- W2068877544 hasRelatedWork W1985841978 @default.
- W2068877544 hasRelatedWork W2012502375 @default.
- W2068877544 hasRelatedWork W2030197842 @default.
- W2068877544 hasRelatedWork W2030582087 @default.
- W2068877544 hasRelatedWork W2039222105 @default.
- W2068877544 hasRelatedWork W2068877544 @default.
- W2068877544 hasRelatedWork W2140787618 @default.
- W2068877544 hasRelatedWork W3093395452 @default.
- W2068877544 hasVolume "33" @default.
- W2068877544 isParatext "false" @default.
- W2068877544 isRetracted "false" @default.
- W2068877544 magId "2068877544" @default.
- W2068877544 workType "article" @default.