Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068903670> ?p ?o ?g. }
- W2068903670 endingPage "134" @default.
- W2068903670 startingPage "128" @default.
- W2068903670 abstract "Hepatic and renal metallothionein (MT) contents were measured in rats following whole-body X-irradiation. When compared with control rats, the hepatic MT-Zn content increased fivefold and MT protein content increased 15-fold by 18 hr following irradiation (2000 rad). Administration of actinomycin-D inhibited both the mobilization of zinc to the liver and the irradiation-induced increase in metallothionein synthesis. Serum zinc levels did not change after irradiation alone, although serum zinc following actinomycin-D treatment and irradiation was significantly elevated. An increase in renal MT-Zn was also observed. In comparison with control, the increase in renal MT-Zn content after irradiation (2000 rad) did not occur earlier than 12 hr but was increased twofold by 24 hr. In comparison with kidney, the hepatic MT-Zn content following irradiation was already elevated threefold by 6 hr. Dose-response studies (250–3000 rad, 72 hr) indicated that similar dose-response relationships for the appearance of MT in the liver and kidney were observed. Total zinc was decreased in the spleen and thymus, and increased in the liver or kidney 18 hr after irradiation (2000 rad). These data indicate that X-ray treatment produces an in vivo induction of hepatic and renal MT synthesis." @default.
- W2068903670 created "2016-06-24" @default.
- W2068903670 creator A5002847343 @default.
- W2068903670 creator A5018523263 @default.
- W2068903670 creator A5058340261 @default.
- W2068903670 creator A5064434536 @default.
- W2068903670 creator A5088820037 @default.
- W2068903670 creator A5090491715 @default.
- W2068903670 creator A5090658047 @default.
- W2068903670 date "1986-09-01" @default.
- W2068903670 modified "2023-09-25" @default.
- W2068903670 title "Increased metallothionein content in rat liver and kidney following X-irradiation" @default.
- W2068903670 cites W1528346173 @default.
- W2068903670 cites W1839823486 @default.
- W2068903670 cites W1969774671 @default.
- W2068903670 cites W1976588543 @default.
- W2068903670 cites W1976726641 @default.
- W2068903670 cites W1982339812 @default.
- W2068903670 cites W1986868377 @default.
- W2068903670 cites W1989466813 @default.
- W2068903670 cites W1992339068 @default.
- W2068903670 cites W1992780022 @default.
- W2068903670 cites W1994385704 @default.
- W2068903670 cites W2000140656 @default.
- W2068903670 cites W2002095261 @default.
- W2068903670 cites W2021632599 @default.
- W2068903670 cites W2028977171 @default.
- W2068903670 cites W2054491767 @default.
- W2068903670 cites W2057864457 @default.
- W2068903670 cites W2058893444 @default.
- W2068903670 cites W2063371107 @default.
- W2068903670 cites W2067775812 @default.
- W2068903670 cites W2085887702 @default.
- W2068903670 cites W2088799928 @default.
- W2068903670 cites W2091602444 @default.
- W2068903670 cites W2093908800 @default.
- W2068903670 cites W2094228621 @default.
- W2068903670 cites W2103199749 @default.
- W2068903670 cites W2145750252 @default.
- W2068903670 cites W2278596438 @default.
- W2068903670 cites W2324927619 @default.
- W2068903670 cites W2332148883 @default.
- W2068903670 cites W2341188235 @default.
- W2068903670 cites W2341400372 @default.
- W2068903670 cites W2495576000 @default.
- W2068903670 cites W58235609 @default.
- W2068903670 cites W1621358600 @default.
- W2068903670 doi "https://doi.org/10.1016/0041-008x(86)90106-7" @default.
- W2068903670 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2429403" @default.
- W2068903670 hasPublicationYear "1986" @default.
- W2068903670 type Work @default.
- W2068903670 sameAs 2068903670 @default.
- W2068903670 citedByCount "49" @default.
- W2068903670 countsByYear W20689036702012 @default.
- W2068903670 countsByYear W20689036702013 @default.
- W2068903670 crossrefType "journal-article" @default.
- W2068903670 hasAuthorship W2068903670A5002847343 @default.
- W2068903670 hasAuthorship W2068903670A5018523263 @default.
- W2068903670 hasAuthorship W2068903670A5058340261 @default.
- W2068903670 hasAuthorship W2068903670A5064434536 @default.
- W2068903670 hasAuthorship W2068903670A5088820037 @default.
- W2068903670 hasAuthorship W2068903670A5090491715 @default.
- W2068903670 hasAuthorship W2068903670A5090658047 @default.
- W2068903670 hasConcept C111337013 @default.
- W2068903670 hasConcept C121332964 @default.
- W2068903670 hasConcept C126322002 @default.
- W2068903670 hasConcept C134018914 @default.
- W2068903670 hasConcept C150903083 @default.
- W2068903670 hasConcept C178790620 @default.
- W2068903670 hasConcept C185544564 @default.
- W2068903670 hasConcept C185592680 @default.
- W2068903670 hasConcept C207001950 @default.
- W2068903670 hasConcept C20719415 @default.
- W2068903670 hasConcept C2780091579 @default.
- W2068903670 hasConcept C2780931953 @default.
- W2068903670 hasConcept C535196362 @default.
- W2068903670 hasConcept C71924100 @default.
- W2068903670 hasConcept C86803240 @default.
- W2068903670 hasConceptScore W2068903670C111337013 @default.
- W2068903670 hasConceptScore W2068903670C121332964 @default.
- W2068903670 hasConceptScore W2068903670C126322002 @default.
- W2068903670 hasConceptScore W2068903670C134018914 @default.
- W2068903670 hasConceptScore W2068903670C150903083 @default.
- W2068903670 hasConceptScore W2068903670C178790620 @default.
- W2068903670 hasConceptScore W2068903670C185544564 @default.
- W2068903670 hasConceptScore W2068903670C185592680 @default.
- W2068903670 hasConceptScore W2068903670C207001950 @default.
- W2068903670 hasConceptScore W2068903670C20719415 @default.
- W2068903670 hasConceptScore W2068903670C2780091579 @default.
- W2068903670 hasConceptScore W2068903670C2780931953 @default.
- W2068903670 hasConceptScore W2068903670C535196362 @default.
- W2068903670 hasConceptScore W2068903670C71924100 @default.
- W2068903670 hasConceptScore W2068903670C86803240 @default.
- W2068903670 hasIssue "2" @default.
- W2068903670 hasLocation W20689036701 @default.
- W2068903670 hasLocation W20689036702 @default.
- W2068903670 hasOpenAccess W2068903670 @default.
- W2068903670 hasPrimaryLocation W20689036701 @default.