Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068910725> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2068910725 endingPage "462" @default.
- W2068910725 startingPage "457" @default.
- W2068910725 abstract "Abstract Summary : Although silent ischemia may be linked to increases in cardiovascular morbidity and mortality, the long‐term effects of a strategy aimed at the detection and treatment of this asymptomatic condition have not been fully explored. We therefore have developed the Atenolol Silent Ischemia Trial (ASIST), the first multicenter, randomized, prospective study of the prognostic implications of silent ischemia in asymptomatic and minimally symptomatic patients with coronary artery disease. Inclusion criteria for study patients were documented coronary artery disease, evidenced angiographically or by previous myocardial infarction, and transient ischemia, evidenced by abnormalities of regional wall motion, stress thallium‐201, or exercise electrocardiogram. The main objective of ASIST is to assess the influence of frequency and duration of symptomatic and asymptomatic ischemic episodes on the occurrence of fatal and nonfatal cardiac events. Atenolol, a beta 1 ‐selective adrenergic blocker, was chosen as the therapeutic intervention because of its potential benefits in treating both symptomatic and asymptomatic ischemia. Ambulatory electrocardiographic monitoring will be used to measure the frequency and duration of ischemic episodes during daily life. The predictive ability of short‐term (4‐week) effects on long‐term (52‐week) response to atenolol treatment is also being assessed, along with the economic impact of this diagnostic and therapeutic strategy. Given the current emphasis on reducing morbidity and mortality associated with coronary artery disease, ASIST results should shed light onto the long‐term management and prognostic implications of this otherwise asymptomatic condition." @default.
- W2068910725 created "2016-06-24" @default.
- W2068910725 creator A5002925912 @default.
- W2068910725 creator A5023061255 @default.
- W2068910725 creator A5065188755 @default.
- W2068910725 creator A5065481567 @default.
- W2068910725 creator A5078294568 @default.
- W2068910725 creator A5082798089 @default.
- W2068910725 creator A5082898423 @default.
- W2068910725 date "1991-06-01" @default.
- W2068910725 modified "2023-09-26" @default.
- W2068910725 title "The Prognostic and Economic Implications of a Strategy to Detect and Treat Asymptomatic Ischemia: The Atenolol Silent Ischemia Trial (ASIST) Protocol" @default.
- W2068910725 cites W1982783727 @default.
- W2068910725 cites W2002263380 @default.
- W2068910725 cites W2009478499 @default.
- W2068910725 cites W2010496427 @default.
- W2068910725 cites W2025089385 @default.
- W2068910725 cites W2052244137 @default.
- W2068910725 cites W2057308145 @default.
- W2068910725 cites W2061971853 @default.
- W2068910725 cites W2068607162 @default.
- W2068910725 cites W2080686773 @default.
- W2068910725 cites W2088227329 @default.
- W2068910725 cites W2136991253 @default.
- W2068910725 cites W2313938778 @default.
- W2068910725 doi "https://doi.org/10.1002/clc.4960140627" @default.
- W2068910725 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1810681" @default.
- W2068910725 hasPublicationYear "1991" @default.
- W2068910725 type Work @default.
- W2068910725 sameAs 2068910725 @default.
- W2068910725 citedByCount "16" @default.
- W2068910725 crossrefType "journal-article" @default.
- W2068910725 hasAuthorship W2068910725A5002925912 @default.
- W2068910725 hasAuthorship W2068910725A5023061255 @default.
- W2068910725 hasAuthorship W2068910725A5065188755 @default.
- W2068910725 hasAuthorship W2068910725A5065481567 @default.
- W2068910725 hasAuthorship W2068910725A5078294568 @default.
- W2068910725 hasAuthorship W2068910725A5082798089 @default.
- W2068910725 hasAuthorship W2068910725A5082898423 @default.
- W2068910725 hasBestOaLocation W20689107251 @default.
- W2068910725 hasConcept C126322002 @default.
- W2068910725 hasConcept C164705383 @default.
- W2068910725 hasConcept C188816634 @default.
- W2068910725 hasConcept C2776525901 @default.
- W2068910725 hasConcept C2777910003 @default.
- W2068910725 hasConcept C2778213512 @default.
- W2068910725 hasConcept C500558357 @default.
- W2068910725 hasConcept C541997718 @default.
- W2068910725 hasConcept C71924100 @default.
- W2068910725 hasConcept C84393581 @default.
- W2068910725 hasConceptScore W2068910725C126322002 @default.
- W2068910725 hasConceptScore W2068910725C164705383 @default.
- W2068910725 hasConceptScore W2068910725C188816634 @default.
- W2068910725 hasConceptScore W2068910725C2776525901 @default.
- W2068910725 hasConceptScore W2068910725C2777910003 @default.
- W2068910725 hasConceptScore W2068910725C2778213512 @default.
- W2068910725 hasConceptScore W2068910725C500558357 @default.
- W2068910725 hasConceptScore W2068910725C541997718 @default.
- W2068910725 hasConceptScore W2068910725C71924100 @default.
- W2068910725 hasConceptScore W2068910725C84393581 @default.
- W2068910725 hasIssue "6" @default.
- W2068910725 hasLocation W20689107251 @default.
- W2068910725 hasLocation W20689107252 @default.
- W2068910725 hasOpenAccess W2068910725 @default.
- W2068910725 hasPrimaryLocation W20689107251 @default.
- W2068910725 hasRelatedWork W1977729419 @default.
- W2068910725 hasRelatedWork W1987215768 @default.
- W2068910725 hasRelatedWork W1995188757 @default.
- W2068910725 hasRelatedWork W2016679923 @default.
- W2068910725 hasRelatedWork W2116001782 @default.
- W2068910725 hasRelatedWork W2273190611 @default.
- W2068910725 hasRelatedWork W2367140913 @default.
- W2068910725 hasRelatedWork W2417414779 @default.
- W2068910725 hasRelatedWork W2790353319 @default.
- W2068910725 hasRelatedWork W4229900919 @default.
- W2068910725 hasVolume "14" @default.
- W2068910725 isParatext "false" @default.
- W2068910725 isRetracted "false" @default.
- W2068910725 magId "2068910725" @default.
- W2068910725 workType "article" @default.