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- W2068921937 abstract "The rate of fatty acid uptake, oxidation, and deposition in skeletal muscles in relation to total and unbound to albumin fatty acids concentration in the medium were investigated in the incubated rat soleus muscle. An immunohistochemical technique was applied to demonstrate whether the albumin-bound fatty acid complex from the medium penetrates well within all areas of the muscle strips. It was found that the percentage of incorporation of palmitic acid into intramuscular lipids was fairly constant, independently of the fatty acid concentration in the medium, and amounted to 6372% for triacylglycerols, 712% for diacylglycerols-monoacylglycerols, and 1926% for phospholipids. Both palmitic acid incorporation into the muscle triacylglycerol stores and its oxidation to CO 2 closely correlated with an increase in both total and unbound to albumin fatty acid concentrations in the incubation medium. Under conditions of increased total but constant unbound to albumin palmitic acid concentrations, the incorporation of palmitic acid into triacylglycerols and its oxidation to CO 2 were also increased, but to a lower extent. This supports the hypothesis that the cellular fatty acid metabolism depends not only on the availability of fatty acids unbound to albumin, but also on the availability of fatty acids complexed to albumin.Key words: skeletal muscle, fatty acids, triacylglycerols, phospholipids." @default.
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- W2068921937 date "2001-08-01" @default.
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- W2068921937 title "Palmitic acid uptake by the rat soleus muscle in vitro" @default.
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- W2068921937 doi "https://doi.org/10.1139/o01-028" @default.
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