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- W2068930147 abstract "Micellar electrokinetic capillary chromatography (MECC) using diode array detection has been investigated for the determination of phase I and phase II metabolites of drugs in biofluids. Methods were optimised for the determination of morphine, morphine-3-glucuronide, morphine-6-glucuronide, normorphine, meclofenamic acid and its metabolites in equine urine. Solid-phase extraction procedure were developed to concentrate and purify the analytes from spiked and post administration urines for MECC analysis. A simple on-line procedure for monitoring the kinetics of hydrolysis of morphine-glucuronide conjugates by beta-glucuronidase was demonstrated." @default.
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- W2068930147 date "1996-09-01" @default.
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- W2068930147 title "Determination of phase II drug metabolites in equine urine by micellar electrokinetic capillary chromatography" @default.
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- W2068930147 doi "https://doi.org/10.1016/0021-9673(96)00380-9" @default.
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