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• W2068947002 startingPage "466" @default.
• W2068947002 abstract "Preclinical and clinical studies of phosphodiesterase 4 inhibitors have shown that these agents may find utility in a wide range of inflammatory disorders, including asthma, chronic obstructive pulmonary disease, atopic dermatitis, rheumatoid arthritis, multiple sclerosis and various neurological disorders. The future of this class of drugs will depend upon the ability to demonstrate a reasonable safety margin against emesis and other typical phosphodieserase (PDE4) side effects, as well as in identification of the inflammatory disorder(s) most relevant to PDE4 inhibition." @default.
• W2068947002 created "2016-06-24" @default.
• W2068947002 creator A5024444227 @default.
• W2068947002 date "1999-08-01" @default.
• W2068947002 modified "2023-10-16" @default.
• W2068947002 title "Phosphodiesterase 4 inhibitors as novel anti-inflammatory agents" @default.
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• W2068947002 doi "https://doi.org/10.1016/s1367-5931(99)80068-4" @default.
• W2068947002 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10419856" @default.
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