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- W2068963802 abstract "For early detection of pathological causes of growth failure proper referral criteria are needed, as well as a thorough clinical, radiological and laboratory assessment. In this minireview we first discuss the two consensus-based and one evidence-based guidelines for referral that have been published. The evidence-based guidelines result in a sensitivity of approximately 80% at a false-positive rate of 2%. Then, relevant clues from the medical history and physical examination are reviewed, and specific investigations based on clinical suspicion listed. In the absence of abnormal clinical findings, an X-ray of the hand/wrist and a laboratory screen are usually performed. Scientific evidence for the various components of laboratory screening is scarce, but accumulated experience and theoretical considerations have led to a list of investigations that may be considered until more evidence is available." @default.
- W2068963802 created "2016-06-24" @default.
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- W2068963802 date "2009-01-01" @default.
- W2068963802 modified "2023-09-30" @default.
- W2068963802 title "Diagnostic Approach in Children with Short Stature" @default.
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- W2068963802 doi "https://doi.org/10.1159/000236082" @default.
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