Matches in SemOpenAlex for { <https://semopenalex.org/work/W2068973313> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W2068973313 endingPage "382" @default.
- W2068973313 startingPage "377" @default.
- W2068973313 abstract "42 consecutive patients with head and neck squamous cell carcinoma were entered into a multi-agent chemotherapy protocol including: bleomycin and Cis-platinum (in continuous infusion), sequenced with methotrexate and Vinblastine (by bolus infusion). Hydroxyurea was substituted for bleomycin when the accumulative dose of bleomycin reached 400 units. 9 of 11 patients with untreated disease responded to chemotherapy, with 36.4% showing complete response following the second cycle. After completion of all therapy, complete response had occurred in 10 patients and partial response in 1. At a median follow-up of 1 year, 9 patients are disease-free, and the median duration of response has not yet been reached. For recurrent disease, the overall regression rate is 45.1% (14/31). The median duration of response is 6.5 months, with responding patients showing a median survival of 8.7 months and non-responders, 5.4 months. The data for response and survival are comparable to previous studies and suggest that toxic manifestations may be mitigated by careful attention to nutrition and production of an anabolic state prior to therapy." @default.
- W2068973313 created "2016-06-24" @default.
- W2068973313 creator A5002015531 @default.
- W2068973313 creator A5042493357 @default.
- W2068973313 creator A5068293926 @default.
- W2068973313 date "1984-01-01" @default.
- W2068973313 modified "2023-09-27" @default.
- W2068973313 title "Continuous Intravenous Infusion Combination Chemotherapy for Head and Neck Squamous Cell Carcinoma" @default.
- W2068973313 doi "https://doi.org/10.1159/000225858" @default.
- W2068973313 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6209601" @default.
- W2068973313 hasPublicationYear "1984" @default.
- W2068973313 type Work @default.
- W2068973313 sameAs 2068973313 @default.
- W2068973313 citedByCount "6" @default.
- W2068973313 crossrefType "journal-article" @default.
- W2068973313 hasAuthorship W2068973313A5002015531 @default.
- W2068973313 hasAuthorship W2068973313A5042493357 @default.
- W2068973313 hasAuthorship W2068973313A5068293926 @default.
- W2068973313 hasConcept C126322002 @default.
- W2068973313 hasConcept C141071460 @default.
- W2068973313 hasConcept C143998085 @default.
- W2068973313 hasConcept C2776232574 @default.
- W2068973313 hasConcept C2776694085 @default.
- W2068973313 hasConcept C2777132456 @default.
- W2068973313 hasConcept C2777546739 @default.
- W2068973313 hasConcept C2781059491 @default.
- W2068973313 hasConcept C2994460389 @default.
- W2068973313 hasConcept C43376680 @default.
- W2068973313 hasConcept C509974204 @default.
- W2068973313 hasConcept C71924100 @default.
- W2068973313 hasConceptScore W2068973313C126322002 @default.
- W2068973313 hasConceptScore W2068973313C141071460 @default.
- W2068973313 hasConceptScore W2068973313C143998085 @default.
- W2068973313 hasConceptScore W2068973313C2776232574 @default.
- W2068973313 hasConceptScore W2068973313C2776694085 @default.
- W2068973313 hasConceptScore W2068973313C2777132456 @default.
- W2068973313 hasConceptScore W2068973313C2777546739 @default.
- W2068973313 hasConceptScore W2068973313C2781059491 @default.
- W2068973313 hasConceptScore W2068973313C2994460389 @default.
- W2068973313 hasConceptScore W2068973313C43376680 @default.
- W2068973313 hasConceptScore W2068973313C509974204 @default.
- W2068973313 hasConceptScore W2068973313C71924100 @default.
- W2068973313 hasIssue "6" @default.
- W2068973313 hasLocation W20689733131 @default.
- W2068973313 hasLocation W20689733132 @default.
- W2068973313 hasOpenAccess W2068973313 @default.
- W2068973313 hasPrimaryLocation W20689733131 @default.
- W2068973313 hasRelatedWork W1565830027 @default.
- W2068973313 hasRelatedWork W2015302134 @default.
- W2068973313 hasRelatedWork W2054366665 @default.
- W2068973313 hasRelatedWork W2162939279 @default.
- W2068973313 hasRelatedWork W2163567381 @default.
- W2068973313 hasRelatedWork W2411807541 @default.
- W2068973313 hasRelatedWork W2431556937 @default.
- W2068973313 hasRelatedWork W2469271394 @default.
- W2068973313 hasRelatedWork W2473581833 @default.
- W2068973313 hasRelatedWork W2418889640 @default.
- W2068973313 hasVolume "41" @default.
- W2068973313 isParatext "false" @default.
- W2068973313 isRetracted "false" @default.
- W2068973313 magId "2068973313" @default.
- W2068973313 workType "article" @default.