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• W2068974538 abstract "Purpose of review Description of the progresses related to the complications and treatment of adult-onset growth hormone deficiency. Recent findings Growth hormone deficiency in adults has gained attention as a clinical syndrome associated with increased morbidity and possibly mortality. Many studies have been conducted on the consequences of growth hormone deficiency and of its replacement, supporting its use in appropriate patients. Early studies were characterized by a high incidence of side effects due to a lack of pilot data to guide appropriate dosing. Given the wide variability in individual responsiveness to growth hormone therapy based on age, sex, and body composition, recent work has been dedicated to understanding which patients derive benefit from therapy, minimizing side effects, and ensuring cost–effectiveness. Summary Long-term prospective trials have shown that growth hormone replacement therapy results in improvements in body composition, dyslipidemia, bone mineral density, and quality of life. The effects on endpoints such as cardiovascular morbidity and mortality and fractures are, however, not fully proven. Randomized trials that compare homogenous groups of growth hormone deficiency patients are still needed. Given the high cost of treatment, dynamic testing for growth hormone deficiency should only be performed in patients in whom there is high clinical suspicion, and therapy should be limited to those with biochemically proven growth hormone deficiency." @default.
• W2068974538 created "2016-06-24" @default.
• W2068974538 creator A5043026082 @default.
• W2068974538 creator A5051572835 @default.
• W2068974538 date "2008-08-01" @default.
• W2068974538 modified "2023-10-17" @default.
• W2068974538 title "Adult-onset growth hormone deficiency: causes, complications and treatment options" @default.
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• W2068974538 cites W1968740548 @default.
• W2068974538 cites W1974798701 @default.
• W2068974538 cites W1976652206 @default.
• W2068974538 cites W1979627788 @default.
• W2068974538 cites W1985024156 @default.
• W2068974538 cites W1989405290 @default.
• W2068974538 cites W1990049523 @default.
• W2068974538 cites W1990257349 @default.
• W2068974538 cites W1991347217 @default.
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• W2068974538 doi "https://doi.org/10.1097/med.0b013e3282ffd97d" @default.
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