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- W2068982893 abstract "Analyses of the fatty acid composition of human plasma non-esterified fatty acids (NEFA) were performed by gas chromatography before and after adrenocorticotropic hormone infusions. The results obtained indicate a significant increase of NEFA, especially of the unsaturated fraction; fatty acid composition of mobilized NEFA differed from that of adipose tissue; it appears that ACTH-sensitive lipase is not the only factor involved in this phenomenon; this hormone is indeed relatively specific for the 1- and 3-triglyceride ester linkages. Therefore, other metabolic pathways are involved, such as monoglyceride lipase and phospholipase activities, undoubtedly associated with selective binding by liver and other tissues. Il a été réalisé, chez 21 sujets, une étude de la composition des AGNE du plasma, par chromatographie en phase gazeuse, avant et après perfusion intra-veineuse de 25 unités d'ACTH en 4 h; l'hormone détermine une élévation significative du taux des AGNE et un enrichissement plus marqué en acides gras insaturés. La composition des acides gras libérés ne coincide pas exactement avec celle, connue, des triglycérides du tissu adipeux et l'on peut montrer qu'aux effets de la lipase “hormone-sensible” du tissu adipeux, activée par l'ACTH et plus spécifique des liaisons ester 1ou 3 (acides gras saturés), s'ajoutent d'autres effets, pouvant être dus à une captation sélective des acides gras par le foie et d'autres tissus, et probablement induits par la libération d'acides gras à partir d'autres processus lipolytiques, tels que celui qui dépendent de la monoglycéride lipase." @default.
- W2068982893 created "2016-06-24" @default.
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- W2068982893 date "1968-05-01" @default.
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- W2068982893 title "Influence de l'hormone adrénocorticotrope sur la composition des acides gras non estérifiés du plasma humain normal" @default.
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- W2068982893 doi "https://doi.org/10.1016/0009-8981(68)90159-9" @default.
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