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- W2069003721 abstract "Letters and Corrections1 November 1989Transfusions and the Acquired Immunodeficiency Syndrome (AIDS)Paul R. Billings, MD, PhDPaul R. Billings, MD, PhDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-111-9-767_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor: The development of the acquired immunodeficiency syndrome (AIDS) in individuals who show serologic evidence of human immunodeficiency virus exposure (HIV) varies among risk groups (1). The prevalence of clinical AIDS in HIV-positive hemophiliacs is lower than that found in HIV-positive nonhemophiliac patients. Hemophiliacs positive for HIV develop significant viremia as a precursor to progressing to clinical AIDS (2). It is not obvious how the genes that produce hemophilia or others closely linked to them might protect HIV-positive hemophiliacs from AIDS or how the common alleles at these loci could promote a more rapid progression from HIV infection...References1. Goedert J, Biggar R, and Weiss S. Three-year incidence of AIDS in five cohorts of HTLV-III-infected risk group members. Science. 1986;231:992-7. CrossrefMedlineGoogle Scholar2. Allain J, Laurian Y, and Paul D. Long-term evaluation of HIV antigen and antibodies to p24 and gp41 in patients with hemophilia: potential clinical importance. N Engl J Med. 1987;317:1114-21. CrossrefMedlineGoogle Scholar3. Nabel G and Baltimore D. An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature. 1987;326:711-3. CrossrefMedlineGoogle Scholar4. Kahan B. Effects of transfusion on recipient immune status: relationship to transplantation. Prog Clin Biol Res. 1985;23:345-74. Google Scholar5. Williams J and Hughes L. Effect of perioperative blood transfusion on recurrence of Crohn's disease. Lancet. 1989;2:131-3. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Paul R. Billings, MD, PhDAffiliations: Harvard Medical School Boston, MA 02215 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 November 1989Volume 111, Issue 9Page: 767-767KeywordsAIDSAllelesHemophiliaHIVHIV infectionsViremia ePublished: 1 December 2008 Issue Published: 1 November 1989 PDF downloadLoading ..." @default.
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- W2069003721 title "Transfusions and the Acquired Immunodeficiency Syndrome (AIDS)" @default.
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