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• W2069014796 abstract "Immunofluorescence studies using PCNA autoantibodies specific for the proliferation-sensitive protein cyclin have revealed dramatic changes in the nuclear distribution of this protein during the S-phase of normal and transformed cells. Patterns of cyclin antigen distribution subdivide S-phase and have provided new cell cycle landmarks. Some of these (nucleolar exclusion or staining), mimic topographical patterns of DNA synthesis thus arguing for a role of this protein in some specific aspect of DNA replication. Cells outside S-phase (G0 included) stain only weakly with PCNA antibodies, stressing the usefulness of this reagent for identifying proliferating cells (S-phase cells) of both normal and malignant origins." @default.
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• W2069014796 date "1986-01-01" @default.
• W2069014796 modified "2023-09-25" @default.
• W2069014796 title "Nuclear patterns of cyclin (PCNA) antigen distribution subdivide S-phase in cultured cells — Some applications of PCNA antibodies" @default.
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• W2069014796 doi "https://doi.org/10.1016/0145-2126(86)90021-4" @default.
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