Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069029258> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2069029258 endingPage "332" @default.
- W2069029258 startingPage "325" @default.
- W2069029258 abstract "Rat band 3 cross-linked carrier erythrocytes have been prepared. Iodinated carbonic anhydrase has been encapsulated into rat erythrocytes. Then, carrier erythrocytes were labeled with 51chromium. Eventually, these doubly labeled rat RBCs were treated with a band 3 cross-linking reagent, namely bis(sulfosuccinimidyl)suberate (BS3). 51Chromium labeling and 125I CA showed to have cytosolic localization in cross-linked carrier erythrocytes. Estimation of the band 3 cross-linking induced by BS3 on rat carrier erythrocytes has been done rendering values around 25% of band 3 monomer reduction. BS3-cross-linked carrier erythrocytes when injected into rats are mainly targeted to liver as shown by chromium labeling localization. Also, encapsulated CA radioactivity carried by cross-linked carrier rat erythrocytes when injected into rats is localized predominantly in liver as shown by in vivo experiments. Accordingly, cross-linked carrier erythrocytes are highly recognized by peritoneal macrophages as detected by in vitro analyses of macrophage recognition. Thus, our data revealed a targeting of carrier rat erythrocytes induced by cross-linking of band 3 protein by BS3. These results support claims in favor of this animal model as a feasible system to analyze cross-linked carrier erythrocytes survival and targeting as well as the in vivo efficacy of targeting of loaded compounds to liver." @default.
- W2069029258 created "2016-06-24" @default.
- W2069029258 creator A5001556889 @default.
- W2069029258 creator A5035553540 @default.
- W2069029258 creator A5052225096 @default.
- W2069029258 creator A5061327354 @default.
- W2069029258 creator A5085014229 @default.
- W2069029258 date "1998-04-01" @default.
- W2069029258 modified "2023-10-14" @default.
- W2069029258 title "In vivo behaviour of rat band 3 cross-linked carrier erythrocytes" @default.
- W2069029258 cites W146114213 @default.
- W2069029258 cites W1481106189 @default.
- W2069029258 cites W1637777503 @default.
- W2069029258 cites W1670348949 @default.
- W2069029258 cites W1972483602 @default.
- W2069029258 cites W1977578489 @default.
- W2069029258 cites W1978064092 @default.
- W2069029258 cites W1981282770 @default.
- W2069029258 cites W1988463307 @default.
- W2069029258 cites W1996771710 @default.
- W2069029258 cites W2014163066 @default.
- W2069029258 cites W2030976439 @default.
- W2069029258 cites W2049833803 @default.
- W2069029258 cites W2070703254 @default.
- W2069029258 cites W2080175289 @default.
- W2069029258 cites W2090760822 @default.
- W2069029258 cites W2100837269 @default.
- W2069029258 cites W2174886163 @default.
- W2069029258 cites W4232648988 @default.
- W2069029258 cites W93255434 @default.
- W2069029258 doi "https://doi.org/10.1016/s0300-9084(98)80075-8" @default.
- W2069029258 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9672753" @default.
- W2069029258 hasPublicationYear "1998" @default.
- W2069029258 type Work @default.
- W2069029258 sameAs 2069029258 @default.
- W2069029258 citedByCount "6" @default.
- W2069029258 countsByYear W20690292582012 @default.
- W2069029258 countsByYear W20690292582015 @default.
- W2069029258 crossrefType "journal-article" @default.
- W2069029258 hasAuthorship W2069029258A5001556889 @default.
- W2069029258 hasAuthorship W2069029258A5035553540 @default.
- W2069029258 hasAuthorship W2069029258A5052225096 @default.
- W2069029258 hasAuthorship W2069029258A5061327354 @default.
- W2069029258 hasAuthorship W2069029258A5085014229 @default.
- W2069029258 hasConcept C12554922 @default.
- W2069029258 hasConcept C144647389 @default.
- W2069029258 hasConcept C150903083 @default.
- W2069029258 hasConcept C153911025 @default.
- W2069029258 hasConcept C181199279 @default.
- W2069029258 hasConcept C185592680 @default.
- W2069029258 hasConcept C202751555 @default.
- W2069029258 hasConcept C207001950 @default.
- W2069029258 hasConcept C2776557347 @default.
- W2069029258 hasConcept C2776589458 @default.
- W2069029258 hasConcept C41625074 @default.
- W2069029258 hasConcept C55493867 @default.
- W2069029258 hasConcept C86803240 @default.
- W2069029258 hasConcept C98539663 @default.
- W2069029258 hasConceptScore W2069029258C12554922 @default.
- W2069029258 hasConceptScore W2069029258C144647389 @default.
- W2069029258 hasConceptScore W2069029258C150903083 @default.
- W2069029258 hasConceptScore W2069029258C153911025 @default.
- W2069029258 hasConceptScore W2069029258C181199279 @default.
- W2069029258 hasConceptScore W2069029258C185592680 @default.
- W2069029258 hasConceptScore W2069029258C202751555 @default.
- W2069029258 hasConceptScore W2069029258C207001950 @default.
- W2069029258 hasConceptScore W2069029258C2776557347 @default.
- W2069029258 hasConceptScore W2069029258C2776589458 @default.
- W2069029258 hasConceptScore W2069029258C41625074 @default.
- W2069029258 hasConceptScore W2069029258C55493867 @default.
- W2069029258 hasConceptScore W2069029258C86803240 @default.
- W2069029258 hasConceptScore W2069029258C98539663 @default.
- W2069029258 hasIssue "4" @default.
- W2069029258 hasLocation W20690292581 @default.
- W2069029258 hasLocation W20690292582 @default.
- W2069029258 hasOpenAccess W2069029258 @default.
- W2069029258 hasPrimaryLocation W20690292581 @default.
- W2069029258 hasRelatedWork W1566729005 @default.
- W2069029258 hasRelatedWork W1700716001 @default.
- W2069029258 hasRelatedWork W2013908504 @default.
- W2069029258 hasRelatedWork W2054843986 @default.
- W2069029258 hasRelatedWork W2116210813 @default.
- W2069029258 hasRelatedWork W2138350991 @default.
- W2069029258 hasRelatedWork W2409285845 @default.
- W2069029258 hasRelatedWork W2434195791 @default.
- W2069029258 hasRelatedWork W2440701365 @default.
- W2069029258 hasRelatedWork W3015376786 @default.
- W2069029258 hasVolume "80" @default.
- W2069029258 isParatext "false" @default.
- W2069029258 isRetracted "false" @default.
- W2069029258 magId "2069029258" @default.
- W2069029258 workType "article" @default.