FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069062127> ?p ?o ?g. }

• W2069062127 endingPage "8" @default.
• W2069062127 startingPage "1" @default.
• W2069062127 abstract "Nonalcoholic fatty liver disease (NAFLD) is considered a hepatic manifestation of metabolic syndrome. In this study, we investigated histological and biochemical changes in NAFLD and the gene expression involving de novo lipogenesis in Otsuka Long-Evans Tokushima fatty (OLETF) rats. We used OLETF rats and Long-Evans Tokushima Otsuka (LETO) rats as animal models of NAFLD and as controls, respectively. Consistent observations were made at 4-week intervals up to 50 weeks of age, and all rats were fed ad libitum with standard food. Biochemical and histological changes were observed, and gene expression involved in de novo lipogenesis was measured using real-time polymerase chain reactions. As a results hepatic micro- and macrovesicular steatosis and hepatocyte ballooning were evident in the OLETF rats at 22–38 weeks of age but disappeared after 42 weeks; no fibrosis or collagen deposition was observed. Gene expression involved in de novo lipogenesis followed a pattern similar to that of the histological changes. In conclusion, in the absence of dietary manipulation, hepatic steatosis in OLETF rats is evident at 22–38 weeks and declines after 42 weeks. Therefore, OLETF rats at 22–38 weeks are recommended as animal models of hepatic steatosis." @default.
• W2069062127 created "2016-06-24" @default.
• W2069062127 creator A5021584969 @default.
• W2069062127 creator A5022870510 @default.
• W2069062127 creator A5031783701 @default.
• W2069062127 creator A5041127618 @default.
• W2069062127 creator A5045493042 @default.
• W2069062127 creator A5049235418 @default.
• W2069062127 creator A5049569161 @default.
• W2069062127 creator A5058505853 @default.
• W2069062127 creator A5065768200 @default.
• W2069062127 date "2013-01-01" @default.
• W2069062127 modified "2023-09-29" @default.
• W2069062127 title "Time Course of the Development of Nonalcoholic Fatty Liver Disease in the Otsuka Long-Evans Tokushima Fatty Rat" @default.
• W2069062127 cites W1630621223 @default.
• W2069062127 cites W1973866760 @default.
• W2069062127 cites W1986838881 @default.
• W2069062127 cites W1992359574 @default.
• W2069062127 cites W1993266217 @default.
• W2069062127 cites W2006694612 @default.
• W2069062127 cites W2011419513 @default.
• W2069062127 cites W2013157141 @default.
• W2069062127 cites W2014052977 @default.
• W2069062127 cites W2021028865 @default.
• W2069062127 cites W2023870084 @default.
• W2069062127 cites W2032878070 @default.
• W2069062127 cites W2040109162 @default.
• W2069062127 cites W2049502491 @default.
• W2069062127 cites W2054019828 @default.
• W2069062127 cites W2057395396 @default.
• W2069062127 cites W2064783558 @default.
• W2069062127 cites W2067987032 @default.
• W2069062127 cites W2083712121 @default.
• W2069062127 cites W2093462070 @default.
• W2069062127 cites W2097553619 @default.
• W2069062127 cites W2098555833 @default.
• W2069062127 cites W2099851474 @default.
• W2069062127 cites W2115914704 @default.
• W2069062127 cites W2126196420 @default.
• W2069062127 cites W2133985126 @default.
• W2069062127 cites W2144178804 @default.
• W2069062127 cites W2147004068 @default.
• W2069062127 cites W2151789007 @default.
• W2069062127 cites W2152513016 @default.
• W2069062127 cites W2154052663 @default.
• W2069062127 cites W2160234571 @default.
• W2069062127 cites W2164017272 @default.
• W2069062127 cites W2165052147 @default.
• W2069062127 cites W2615637571 @default.
• W2069062127 cites W38571946 @default.
• W2069062127 cites W4248842722 @default.
• W2069062127 cites W4296816736 @default.
• W2069062127 cites W4376848364 @default.
• W2069062127 doi "https://doi.org/10.1155/2013/342648" @default.
• W2069062127 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3666266" @default.
• W2069062127 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23737763" @default.
• W2069062127 hasPublicationYear "2013" @default.
• W2069062127 type Work @default.
• W2069062127 sameAs 2069062127 @default.
• W2069062127 citedByCount "25" @default.
• W2069062127 countsByYear W20690621272014 @default.
• W2069062127 countsByYear W20690621272015 @default.
• W2069062127 countsByYear W20690621272016 @default.
• W2069062127 countsByYear W20690621272018 @default.
• W2069062127 countsByYear W20690621272019 @default.
• W2069062127 countsByYear W20690621272020 @default.
• W2069062127 countsByYear W20690621272021 @default.
• W2069062127 countsByYear W20690621272022 @default.
• W2069062127 countsByYear W20690621272023 @default.
• W2069062127 crossrefType "journal-article" @default.
• W2069062127 hasAuthorship W2069062127A5021584969 @default.
• W2069062127 hasAuthorship W2069062127A5022870510 @default.
• W2069062127 hasAuthorship W2069062127A5031783701 @default.
• W2069062127 hasAuthorship W2069062127A5041127618 @default.
• W2069062127 hasAuthorship W2069062127A5045493042 @default.
• W2069062127 hasAuthorship W2069062127A5049235418 @default.
• W2069062127 hasAuthorship W2069062127A5049569161 @default.
• W2069062127 hasAuthorship W2069062127A5058505853 @default.
• W2069062127 hasAuthorship W2069062127A5065768200 @default.
• W2069062127 hasBestOaLocation W20690621271 @default.
• W2069062127 hasConcept C126322002 @default.
• W2069062127 hasConcept C134018914 @default.
• W2069062127 hasConcept C141359234 @default.
• W2069062127 hasConcept C202751555 @default.
• W2069062127 hasConcept C2776175330 @default.
• W2069062127 hasConcept C2776200302 @default.
• W2069062127 hasConcept C2776954865 @default.
• W2069062127 hasConcept C2778772119 @default.
• W2069062127 hasConcept C2779134260 @default.
• W2069062127 hasConcept C4733338 @default.
• W2069062127 hasConcept C55493867 @default.
• W2069062127 hasConcept C71924100 @default.
• W2069062127 hasConcept C86803240 @default.
• W2069062127 hasConceptScore W2069062127C126322002 @default.
• W2069062127 hasConceptScore W2069062127C134018914 @default.
• W2069062127 hasConceptScore W2069062127C141359234 @default.
• W2069062127 hasConceptScore W2069062127C202751555 @default.
• W2069062127 hasConceptScore W2069062127C2776175330 @default.

• next