Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069067703> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2069067703 endingPage "151a" @default.
- W2069067703 startingPage "151a" @default.
- W2069067703 abstract "The outer membrane of Gram-negative bacteria is a protective diffusion barrier preventing the free entry of solutes into the periplasm. At the same time, the embedded proteins (Omp's for Outer Membrane Proteins) fulfil a number of tasks that are crucial to the bacterial cell, such as solute and protein translocation, as well as signal transduction. Since a large number of years, a lot of simple membranar models with synthetic lipids such as POPC, POPG, DMPG….allowed scientists to better understand porin insertions and antibiotic translocation/interaction. As any molecular phenomena, it is better to study it in their own environment. With the availability of well characterized E.coli total lipid extract phospholipids, in vitro model membranes such as liposomes and proteoliposomes can be created and antibiotic translocation investigated in a bacterial environment, as close as possible to the existing membranes.In this study, the effects of porins on the structural order of lipid membranes was investigated by measuring, as a function of temperature, the steady-state fluorescence anisotropy (rS) of TMA-DPH and DPH incorporated into liposomes and proteoliposomes of E.coli total lipid extract phospholipids. DPH, embedded in the bilayer, can give informations about lipid diffusion. TMA-DPH, anchored at the aqueous interface of the phospholipid bilayer, allow us to better understand Omp's/antibiotic interactions.By using those probes, we were able to obtain information on the effects caused by the insertion of Omp's into the core and at the interface regions of the bilayer. This information, correlated with other membrane models, can be of considerable interest in establishing a possible relationship between the lipid composition of the phospholipid bilayer surface and antibiotic translocation." @default.
- W2069067703 created "2016-06-24" @default.
- W2069067703 creator A5030869192 @default.
- W2069067703 creator A5044641712 @default.
- W2069067703 creator A5053021665 @default.
- W2069067703 creator A5075647902 @default.
- W2069067703 date "2009-02-01" @default.
- W2069067703 modified "2023-09-29" @default.
- W2069067703 title "Liposome Steady-state Anisotropy Of E.coli Total Lipid Extracts: A Tool To Better Understand Antibiotic Translocation In A Bacterial Environment" @default.
- W2069067703 doi "https://doi.org/10.1016/j.bpj.2008.12.679" @default.
- W2069067703 hasPublicationYear "2009" @default.
- W2069067703 type Work @default.
- W2069067703 sameAs 2069067703 @default.
- W2069067703 citedByCount "0" @default.
- W2069067703 crossrefType "journal-article" @default.
- W2069067703 hasAuthorship W2069067703A5030869192 @default.
- W2069067703 hasAuthorship W2069067703A5044641712 @default.
- W2069067703 hasAuthorship W2069067703A5053021665 @default.
- W2069067703 hasAuthorship W2069067703A5075647902 @default.
- W2069067703 hasBestOaLocation W20690677031 @default.
- W2069067703 hasConcept C104317684 @default.
- W2069067703 hasConcept C12554922 @default.
- W2069067703 hasConcept C130316041 @default.
- W2069067703 hasConcept C146587185 @default.
- W2069067703 hasConcept C185154212 @default.
- W2069067703 hasConcept C185592680 @default.
- W2069067703 hasConcept C192157962 @default.
- W2069067703 hasConcept C201663137 @default.
- W2069067703 hasConcept C2777317804 @default.
- W2069067703 hasConcept C2778918659 @default.
- W2069067703 hasConcept C2780943371 @default.
- W2069067703 hasConcept C39944091 @default.
- W2069067703 hasConcept C41625074 @default.
- W2069067703 hasConcept C547475151 @default.
- W2069067703 hasConcept C55493867 @default.
- W2069067703 hasConcept C86803240 @default.
- W2069067703 hasConceptScore W2069067703C104317684 @default.
- W2069067703 hasConceptScore W2069067703C12554922 @default.
- W2069067703 hasConceptScore W2069067703C130316041 @default.
- W2069067703 hasConceptScore W2069067703C146587185 @default.
- W2069067703 hasConceptScore W2069067703C185154212 @default.
- W2069067703 hasConceptScore W2069067703C185592680 @default.
- W2069067703 hasConceptScore W2069067703C192157962 @default.
- W2069067703 hasConceptScore W2069067703C201663137 @default.
- W2069067703 hasConceptScore W2069067703C2777317804 @default.
- W2069067703 hasConceptScore W2069067703C2778918659 @default.
- W2069067703 hasConceptScore W2069067703C2780943371 @default.
- W2069067703 hasConceptScore W2069067703C39944091 @default.
- W2069067703 hasConceptScore W2069067703C41625074 @default.
- W2069067703 hasConceptScore W2069067703C547475151 @default.
- W2069067703 hasConceptScore W2069067703C55493867 @default.
- W2069067703 hasConceptScore W2069067703C86803240 @default.
- W2069067703 hasIssue "3" @default.
- W2069067703 hasLocation W20690677031 @default.
- W2069067703 hasOpenAccess W2069067703 @default.
- W2069067703 hasPrimaryLocation W20690677031 @default.
- W2069067703 hasRelatedWork W1137376477 @default.
- W2069067703 hasRelatedWork W1966281881 @default.
- W2069067703 hasRelatedWork W1972846085 @default.
- W2069067703 hasRelatedWork W2037926535 @default.
- W2069067703 hasRelatedWork W2051926816 @default.
- W2069067703 hasRelatedWork W2062726752 @default.
- W2069067703 hasRelatedWork W2064011548 @default.
- W2069067703 hasRelatedWork W2086496775 @default.
- W2069067703 hasRelatedWork W2096077577 @default.
- W2069067703 hasRelatedWork W2097151906 @default.
- W2069067703 hasRelatedWork W2124079657 @default.
- W2069067703 hasRelatedWork W2319803840 @default.
- W2069067703 hasRelatedWork W2496306851 @default.
- W2069067703 hasRelatedWork W2964110764 @default.
- W2069067703 hasRelatedWork W2966424406 @default.
- W2069067703 hasRelatedWork W3084580243 @default.
- W2069067703 hasRelatedWork W3112747416 @default.
- W2069067703 hasRelatedWork W3149738448 @default.
- W2069067703 hasRelatedWork W3198012723 @default.
- W2069067703 hasRelatedWork W2340590315 @default.
- W2069067703 hasVolume "96" @default.
- W2069067703 isParatext "false" @default.
- W2069067703 isRetracted "false" @default.
- W2069067703 magId "2069067703" @default.
- W2069067703 workType "article" @default.