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• W2069111444 abstract "Hepatitis C virus infects almost 170 million people per year but its assembly pathway, architecture and the structures of its envelope proteins are poorly understood. Using electron tomography of plastic-embedded sections of insect cells, we have visualized the morphogenesis of recombinant Hepatitis C virus-like particles. Our data provide a three-dimensional sketch of viral assembly at the endoplasmic reticulum showing different budding stages and contiguity of buds. This latter phenomenon could play an important role during the assembly of wt-HCV and explain the size-heterogeneity of its particles." @default.
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• W2069111444 date "2012-09-01" @default.
• W2069111444 modified "2023-10-03" @default.
• W2069111444 title "Three-dimensional visualization of forming Hepatitis C virus-like particles by electron-tomography" @default.
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• W2069111444 doi "https://doi.org/10.1016/j.virol.2012.05.001" @default.
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