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• W2069111505 abstract "Abstract An examination of chromosome structure using both scanning and transmission electron microscopy is reported. The principal study is based on whole chromosomes obtained by established mass-isolation techniques from Hela cells and mouse ascitic tumour cells. Preparations mounted on glass and studied with the scanning electron microscope were found to provide valuable information on the coarse sub-structure of whole chromosomes. Observations with the transmission electron microscope were gained from whole chromosome replicas. It is demonstrated that replicas, obtained from isolated chromosomes, allow observations of total configuration without the limitations inherent in the techniques commonly employed in the electron microscopy of chromosomes." @default.
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• W2069111505 date "1970-01-01" @default.
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• W2069111505 title "The application of scanning and transmission electron microscopy to a study of whole chromosomes" @default.
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• W2069111505 doi "https://doi.org/10.1016/0047-7206(70)90044-0" @default.
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