Matches in SemOpenAlex for { <https://semopenalex.org/work/W2069116952> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2069116952 endingPage "1089" @default.
- W2069116952 startingPage "1083" @default.
- W2069116952 abstract "This study was designed to test the hypothesis that conversion of atrial flutter in humans by ibutilide, a new class III antiarrhythmic agent, is characterized by an increase in atrial cycle length variability. Conversion of tachyarrhythmias has been associated with increased oscillations of cycle length. Electrograms and monophasic action potentials from the fight atrium in 35 patients with spontaneous, sustained atrial flutter were recorded before, during and after intravenous ibutilide (0.005 to 0.025 mg/kg body weight, n = 25) or placebo (n = 10). Atrial cycle length, cycle length variability (coefficient of variation), diastolic interval and diastolic interval variability were measured from 10 consecutive cycles at baseline and 3 min before, 1 min before, 30 s before and immediately before conversion. Similar measurements were made in patients who received ibutilide or placebo but did not convert. Ibutilide converted atrial flutter in 14 of 25 patients 25 ± 16 min (mean ± SD) after initiation of the infusion, whereas placebo converted no patients. Atrial cycle length was prolonged to the same extent in ibutilide converters and nonconverters (36 ± 19 vs. 38 ± 21 ms, p = NS) and was not affected by placebo. Beat-to-beat variability in atrial cycle length (baseline 1.2 ± 0.7 vs. preconversion 7.3 ± 4.9, p < 0.01) and diastolic interval (baseline 11 ± 8 vs. preconversion 33 ± 23, p < 0.05) increased significantly just before atrial flutter conversion and remained unchanged in ibutilide nonconverters and placebo group patients. Ibutilide prolongs atrial flutter cycle length, but conversion of atrial flutter by ibutilide is characterized by increased variability in atrial cycle length and diastolic interval." @default.
- W2069116952 created "2016-06-24" @default.
- W2069116952 creator A5011434213 @default.
- W2069116952 creator A5059101841 @default.
- W2069116952 creator A5066843009 @default.
- W2069116952 creator A5089152067 @default.
- W2069116952 date "1996-04-01" @default.
- W2069116952 modified "2023-10-18" @default.
- W2069116952 title "Conversion of atrial flutter by ibutilide is associated with increased atrial cycle length variability" @default.
- W2069116952 cites W1602261419 @default.
- W2069116952 cites W1981511443 @default.
- W2069116952 cites W1995340775 @default.
- W2069116952 cites W2006050091 @default.
- W2069116952 cites W2019425345 @default.
- W2069116952 cites W2025206153 @default.
- W2069116952 cites W2036423321 @default.
- W2069116952 cites W2039935313 @default.
- W2069116952 cites W2040806336 @default.
- W2069116952 cites W2041298964 @default.
- W2069116952 cites W2046325894 @default.
- W2069116952 cites W2050628613 @default.
- W2069116952 cites W2054435562 @default.
- W2069116952 cites W2059716861 @default.
- W2069116952 cites W2061513139 @default.
- W2069116952 cites W2062889210 @default.
- W2069116952 cites W2076724991 @default.
- W2069116952 cites W2080542032 @default.
- W2069116952 cites W2091210387 @default.
- W2069116952 cites W2100769598 @default.
- W2069116952 cites W2153067161 @default.
- W2069116952 cites W2220988442 @default.
- W2069116952 cites W2425431627 @default.
- W2069116952 doi "https://doi.org/10.1016/0735-1097(95)00607-9" @default.
- W2069116952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8609325" @default.
- W2069116952 hasPublicationYear "1996" @default.
- W2069116952 type Work @default.
- W2069116952 sameAs 2069116952 @default.
- W2069116952 citedByCount "55" @default.
- W2069116952 countsByYear W20691169522012 @default.
- W2069116952 countsByYear W20691169522013 @default.
- W2069116952 countsByYear W20691169522018 @default.
- W2069116952 crossrefType "journal-article" @default.
- W2069116952 hasAuthorship W2069116952A5011434213 @default.
- W2069116952 hasAuthorship W2069116952A5059101841 @default.
- W2069116952 hasAuthorship W2069116952A5066843009 @default.
- W2069116952 hasAuthorship W2069116952A5089152067 @default.
- W2069116952 hasConcept C126322002 @default.
- W2069116952 hasConcept C142724271 @default.
- W2069116952 hasConcept C164705383 @default.
- W2069116952 hasConcept C204787440 @default.
- W2069116952 hasConcept C27081682 @default.
- W2069116952 hasConcept C2778292772 @default.
- W2069116952 hasConcept C2779161974 @default.
- W2069116952 hasConcept C2779215400 @default.
- W2069116952 hasConcept C42219234 @default.
- W2069116952 hasConcept C57900726 @default.
- W2069116952 hasConcept C71924100 @default.
- W2069116952 hasConcept C84393581 @default.
- W2069116952 hasConceptScore W2069116952C126322002 @default.
- W2069116952 hasConceptScore W2069116952C142724271 @default.
- W2069116952 hasConceptScore W2069116952C164705383 @default.
- W2069116952 hasConceptScore W2069116952C204787440 @default.
- W2069116952 hasConceptScore W2069116952C27081682 @default.
- W2069116952 hasConceptScore W2069116952C2778292772 @default.
- W2069116952 hasConceptScore W2069116952C2779161974 @default.
- W2069116952 hasConceptScore W2069116952C2779215400 @default.
- W2069116952 hasConceptScore W2069116952C42219234 @default.
- W2069116952 hasConceptScore W2069116952C57900726 @default.
- W2069116952 hasConceptScore W2069116952C71924100 @default.
- W2069116952 hasConceptScore W2069116952C84393581 @default.
- W2069116952 hasIssue "5" @default.
- W2069116952 hasLocation W20691169521 @default.
- W2069116952 hasLocation W20691169522 @default.
- W2069116952 hasOpenAccess W2069116952 @default.
- W2069116952 hasPrimaryLocation W20691169521 @default.
- W2069116952 hasRelatedWork W1559958385 @default.
- W2069116952 hasRelatedWork W2047344647 @default.
- W2069116952 hasRelatedWork W2096338776 @default.
- W2069116952 hasRelatedWork W2352964226 @default.
- W2069116952 hasRelatedWork W2357544290 @default.
- W2069116952 hasRelatedWork W2376011722 @default.
- W2069116952 hasRelatedWork W2409916269 @default.
- W2069116952 hasRelatedWork W3029954288 @default.
- W2069116952 hasRelatedWork W4244318441 @default.
- W2069116952 hasRelatedWork W4246591656 @default.
- W2069116952 hasVolume "27" @default.
- W2069116952 isParatext "false" @default.
- W2069116952 isRetracted "false" @default.
- W2069116952 magId "2069116952" @default.
- W2069116952 workType "article" @default.